HRPA_PECAS
ID HRPA_PECAS Reviewed; 68 AA.
AC Q6RK33; Q6D5E7;
DT 07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 79.
DE RecName: Full=Hrp pili protein HrpA;
DE AltName: Full=TTSS pilin HrpA;
GN Name=hrpA; OrderedLocusNames=ECA2093;
OS Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS carotovora subsp. atroseptica).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Pectobacterium.
OX NCBI_TaxID=218491;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=SCRI 1039 / ATCC BAA-673;
RX PubMed=15384484; DOI=10.1094/mpmi.2004.17.9.943;
RA Holeva M.C., Bell K.S., Hyman L.J., Avrova A.O., Whisson S.C., Birch P.R.,
RA Toth I.K.;
RT "Use of a pooled transposon mutation grid to demonstrate roles in disease
RT development for Erwinia carotovora subsp. atroseptica putative type III
RT secreted effector (DspE/A) and helper (HrpN) proteins.";
RL Mol. Plant Microbe Interact. 17:943-950(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCRI 1043 / ATCC BAA-672;
RX PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT subsp. atroseptica and characterization of virulence factors.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC -!- FUNCTION: Major structure protein of the hrp pilus, which is a
CC component of the type III secretion system (TTSS, Hrp secretion system)
CC required for effector protein delivery, parasitism, and pathogenicity.
CC The hrp pilus functions as a conduit for protein delivery into the host
CC cell (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Fimbrium {ECO:0000250}.
CC Note=Extracellular and secreted via type III secretion system.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the HrpA type 2 family. {ECO:0000305}.
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DR EMBL; AY496066; AAS20371.1; -; Genomic_DNA.
DR EMBL; BX950851; CAG74995.1; -; Genomic_DNA.
DR RefSeq; WP_009112561.1; NC_004547.2.
DR AlphaFoldDB; Q6RK33; -.
DR STRING; 218491.ECA2093; -.
DR EnsemblBacteria; CAG74995; CAG74995; ECA2093.
DR GeneID; 51389509; -.
DR GeneID; 61408171; -.
DR KEGG; eca:ECA2093; -.
DR eggNOG; ENOG5033M1A; Bacteria.
DR HOGENOM; CLU_188357_1_0_6; -.
DR OMA; SITDGQM; -.
DR OrthoDB; 2057498at2; -.
DR Proteomes; UP000007966; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Fimbrium; Reference proteome; Secreted; Virulence.
FT CHAIN 1..68
FT /note="Hrp pili protein HrpA"
FT /id="PRO_0000226253"
SQ SEQUENCE 68 AA; 6841 MW; D378C7E55F8F736A CRC64;
MALGLSQVAS QAASQTLDTA MAGSLTRAAG AQAQKIALDT ENSILDGQMD SASKSLNSGQ
KAAKAIQF