ID   HRPA_PSESG              Reviewed;         108 AA.
AC   Q52480; Q6L954;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Hrp pili protein HrpA;
DE   AltName: Full=TTSS pilin HrpA;
GN   Name=hrpA;
OS   Pseudomonas savastanoi pv. glycinea (Pseudomonas syringae pv. glycinea).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=318;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Race 4;
RX   PubMed=7579616; DOI=10.1094/mpmi-8-0717;
RA   Preston G., Huang H.-C., He S.Y., Collmer A.;
RT   "The HrpZ proteins of Pseudomonas syringae pvs. syringae, glycinea, and
RT   tomato are encoded by an operon containing Yersinia ysc homologs and elicit
RT   the hypersensitive response in tomato but not soybean.";
RL   Mol. Plant Microbe Interact. 8:717-732(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=r0;
RA   Inoue Y., Takikawa Y.;
RT   "Phylogenic analysis of DNA sequences around the hrpZ regions of
RT   Pseudomonas syringae.";
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Major structural protein of the hrp pilus, which is a
CC       component of the type III secretion system (TTSS, Hrp secretion system)
CC       required for effector protein delivery, parasitism, and pathogenicity.
CC       The hrp pilus functions as a conduit for protein delivery into the host
CC       cell. Also, affects the expression of TTSS-associated genes. Required
CC       for full expression of genes that encode regulatory, secretion, and
CC       effector proteins of the TTSS. HrpA-mediated gene regulation apparently
CC       is through effect on the mRNA level of hrpR and hrpS (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Fimbrium {ECO:0000250}.
CC       Note=Extracellular and secreted via type III secretion system.
CC       {ECO:0000250}.
CC   -!- INDUCTION: Expression enhanced by contact with host cell wall. Also
CC       regulated by HrpRS and HrpL (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HrpA type 1 family. {ECO:0000305}.
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DR   EMBL; L41862; AAB00135.1; -; Genomic_DNA.
DR   EMBL; AB112554; BAD20827.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q52480; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Fimbrium; Secreted; Virulence.
FT   CHAIN           1..108
FT                   /note="Hrp pili protein HrpA"
FT                   /id="PRO_0000219572"
FT   REGION          41..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..58
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         61
FT                   /note="P -> K (in strain: r0)"
SQ   SEQUENCE   108 AA;  11115 MW;  25B96DC377C3BBA7 CRC64;
     MSIISSLTNA GRGVVNTVGG AAQGINSVKS SADRNIALTK NTGSTDSIDA TRSSISKGDA
     PSAELDGTAN EENGLLRETS MLAGFEDKKE ALSNQIVASK IRNSVVQF