HRPB_RALSO
ID HRPB_RALSO Reviewed; 477 AA.
AC P31778;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1993, sequence version 1.
DT 25-MAY-2022, entry version 137.
DE RecName: Full=Regulatory protein HrpB;
GN Name=hrpB; OrderedLocusNames=RSp0873; ORFNames=RS01644;
OS Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OG Plasmid megaplasmid Rsp.
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=267608;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=GMI1000;
RX PubMed=1479894; DOI=10.1111/j.1365-2958.1992.tb01764.x;
RA Genin S., Gough C.L., Zischek C., Boucher C.A.;
RT "Evidence that the hrpB gene encodes a positive regulator of pathogenicity
RT genes from Pseudomonas solanacearum.";
RL Mol. Microbiol. 6:3065-3076(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GMI1000;
RX PubMed=11823852; DOI=10.1038/415497a;
RA Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL Nature 415:497-502(2002).
CC -!- FUNCTION: Positive regulation of hypersensitive response genes involved
CC in plant pathogenicity and partly of its own synthesis in minimal
CC medium.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJ245811; CAB58260.1; -; Genomic_DNA.
DR EMBL; AL646053; CAD18024.1; -; Genomic_DNA.
DR PIR; S28010; S28010.
DR RefSeq; WP_011004170.1; NC_003296.1.
DR AlphaFoldDB; P31778; -.
DR SMR; P31778; -.
DR STRING; 267608.RSp0873; -.
DR EnsemblBacteria; CAD18024; CAD18024; RSp0873.
DR GeneID; 60503781; -.
DR KEGG; rso:RSp0873; -.
DR eggNOG; COG2207; Bacteria.
DR HOGENOM; CLU_573568_0_0_4; -.
DR OMA; YLYCRAK; -.
DR PHI-base; PHI:7462; -.
DR Proteomes; UP000001436; Plasmid megaplasmid Rsp.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEP:CollecTF.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR Pfam; PF12833; HTH_18; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 4: Predicted;
KW Activator; DNA-binding; Hypersensitive response elicitation; Plasmid;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..477
FT /note="Regulatory protein HrpB"
FT /id="PRO_0000194525"
FT DOMAIN 375..477
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 393..414
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 444..467
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ SEQUENCE 477 AA; 53268 MW; D4E5FECA713A511B CRC64;
MLGNIYFALA SGLAARERLP EYANAVFAAD FDRAYQLVDH HSSQRGKSDD YAGVLAMADA
SLLLECDEEA EEGFRLAQRL IRHSDDQLRV VSCRNTGWQA LLRDRYAAAA SCFSRMAEDD
GATWTQQVEG LIGLALVHHQ LGQQDASDDA LRAAREAADG RSDRGWLATI DLIIYEFAVQ
AGIRCSNRLL EHAFWQSAEM GATLLANHGG RNGWTPTVSQ GVPMPALIQR RAEYLSLLRR
MADGDRAAID PLMATLNHSR KLGSRLLMQT KVEVVLAALS GEQYDVAGRV FDQICNRETT
YGARRWNFDF LYCRAKMAAQ RGDAAGALKF YTTYMQDALR CLRTETVNVR RASAAVPVAS
RASDDVSARL SAKYRRAYRY IIENIERSDL TTREVAAHIN VTERALQLAF KSAVGMSPSS
VIRRMRLEGI RSDLLDSERN PSNIIDTASR WGIRSRSALV KGYRKQFNEA PSETIWR
