ID   HRPN_ERWAM              Reviewed;         403 AA.
AC   Q01099;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 3.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Harpin HrpN;
DE   AltName: Full=Harpin-Ea;
GN   Name=hrpN;
OS   Erwinia amylovora (Fire blight bacteria).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Erwinia.
OX   NCBI_TaxID=552;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-15.
RC   STRAIN=Ea321;
RX   PubMed=1621099; DOI=10.1126/science.1621099;
RA   Wei Z.-M., Laby R.J., Zumoff C.H., Bauer D.W., He S.Y., Collmer A.,
RA   Beer S.V.;
RT   "Harpin, elicitor of the hypersensitive response produced by the plant
RT   pathogen Erwinia amylovora.";
RL   Science 257:85-88(1992).
RN   [2]
RP   SEQUENCE REVISION.
RA   Laby R.J., Kim J.F., Beer S.V.;
RL   Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Elicits the hypersensitive response (HR) in the plant upon
CC       infection. Harpin elicits HR in non-hosts and is also required for
CC       pathogenicity in host plants.
CC   -!- SUBCELLULAR LOCATION: Secreted. Note=Via the HRP secretion pathway.
CC   -!- SIMILARITY: Belongs to the harpin HrpN family. {ECO:0000305}.
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DR   EMBL; M92994; AAC31644.2; -; Genomic_DNA.
DR   PIR; T08471; T08471.
DR   RefSeq; WP_004155369.1; NZ_RQKG01000002.1.
DR   AlphaFoldDB; Q01099; -.
DR   GeneID; 8913118; -.
DR   PATRIC; fig|665029.3.peg.571; -.
DR   PHI-base; PHI:2467; -.
DR   PHI-base; PHI:2475; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR   InterPro; IPR006961; HrpN/Z.
DR   Pfam; PF04877; Harpin; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hypersensitive response elicitation; Secreted.
FT   CHAIN           1..403
FT                   /note="Harpin HrpN"
FT                   /id="PRO_0000084067"
FT   REGION          113..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          173..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        173..192
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   403 AA;  39697 MW;  146FA642351D8E87 CRC64;
     MSLNTSGLGA STMQISIGGA GGNNGLLGTS RQNAGLGGNS ALGLGGGNQN DTVNQLAGLL
     TGMMMMMSMM GGGGLMGGGL GGGLGNGLGG SGGLGEGLSN ALNDMLGGSL NTLGSKGGNN
     TTSTTNSPLD QALGINSTSQ NDDSTSGTDS TSDSSDPMQQ LLKMFSEIMQ SLFGDGQDGT
     QGSSSGGKQP TEGEQNAYKK GVTDALSGLM GNGLSQLLGN GGLGGGQGGN AGTGLDGSSL
     GGKGLQNLSG PVDYQQLGNA VGTGIGMKAG IQALNDIGTH SDSSTRSFVN KGDRAMAKEI
     GQFMDQYPEV FGKPQYQKGP GQEVKTDDKS WAKALSKPDD DGMTPASMEQ FNKAKGMIKS
     AMAGDTGNGN LQARGAGGSS LGIDAMMAGD AINNMALGKL GAA