ID   HRPR_PSESY              Reviewed;         314 AA.
AC   P37930;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Pathogenicity locus probable regulatory protein HrpR;
GN   Name=hrpR;
OS   Pseudomonas syringae pv. syringae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Pss61;
RX   PubMed=8106313; DOI=10.1128/jb.176.4.1025-1036.1994;
RA   Xiao Y., Heu S., Yi J., Lu Y., Hutcheson S.W.;
RT   "Identification of a putative alternate sigma factor and characterization
RT   of a multicomponent regulatory cascade controlling the expression of
RT   Pseudomonas syringae pv. syringae Pss61 hrp and hrmA genes.";
RL   J. Bacteriol. 176:1025-1036(1994).
CC   -!- FUNCTION: Member of the two-component regulatory system HrpR/HrpS that
CC       regulates the activation of the sigma factor hrpL which itself induces
CC       the expression of hprD as well as other hrp loci which are involved in
CC       plant pathogenicity, hrmA and avr genes. Probably interacts with sigma-
CC       54.
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DR   EMBL; U03853; AAA17651.1; -; Unassigned_DNA.
DR   PIR; A49889; A49889.
DR   AlphaFoldDB; P37930; -.
DR   SMR; P37930; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR   InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR   Pfam; PF02954; HTH_8; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR   PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   4: Predicted;
KW   Activator; ATP-binding; DNA-binding; Hypersensitive response elicitation;
KW   Nucleotide-binding; Transcription; Transcription regulation;
KW   Two-component regulatory system.
FT   CHAIN           1..314
FT                   /note="Pathogenicity locus probable regulatory protein
FT                   HrpR"
FT                   /id="PRO_0000081321"
FT   DOMAIN          11..239
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   DNA_BIND        281..300
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255"
FT   BINDING         39..46
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   BINDING         101..110
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
SQ   SEQUENCE   314 AA;  34802 MW;  A635CE2309BEB0C7 CRC64;
     MSTDIDNDVR TRWNVTALSA GHQIAMHSAL LDMDLLLCGE TGTGKDTLAS RIHELSSRTG
     PFVGMNCAAI PESLAESQLF GVVNGAFTGV CRAREGYIEP SNGGTLYLDE IDTMPLSLQA
     KLLRVLESRG VERLGSTDFI PLDLQVIASA SAPLDELVEQ GLFRRDLFFR LNVLTLQLPA
     LRKRREQILP LFDQFTQDIA AECGRSAPTL DNGRVQILLS HDWPGNVREL KSAANAICPR
     IAVAGRRAVE ARDPVTGLRM QMRVIEKMLI QDALKRHRHN FDAVLEELEL PRRTLYHRMK
     ELGVASHIDL AAES