HRPS_PSESH
ID HRPS_PSESH Reviewed; 302 AA.
AC P26316;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 2.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Pathogenicity locus probable regulatory protein HrpS;
GN Name=hrpS;
OS Pseudomonas savastanoi pv. phaseolicola (Pseudomonas syringae pv.
OS phaseolicola).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=319;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2768197; DOI=10.1128/jb.171.9.5031-5038.1989;
RA Grimm C., Panopoulos N.J.;
RT "The predicted protein product of a pathogenicity locus from Pseudomonas
RT syringae pv. phaseolicola is homologous to a highly conserved domain of
RT several procaryotic regulatory proteins.";
RL J. Bacteriol. 171:5031-5038(1989).
CC -!- FUNCTION: Member of the two-component regulatory system HrpR/HrpS that
CC regulates the activation of the sigma factor hrpL which itself induces
CC the expression of hprD as well as other hrp loci which are involved in
CC plant pathogenicity, hrmA and avr genes. Probably interacts with sigma-
CC 54.
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DR EMBL; M28524; AAA25838.1; -; Genomic_DNA.
DR PIR; A33964; A33964.
DR AlphaFoldDB; P26316; -.
DR SMR; P26316; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0034053; P:modulation by symbiont of host defense-related programmed cell death; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW Activator; ATP-binding; DNA-binding; Hypersensitive response elicitation;
KW Nucleotide-binding; Transcription; Transcription regulation;
KW Two-component regulatory system.
FT CHAIN 1..302
FT /note="Pathogenicity locus probable regulatory protein
FT HrpS"
FT /id="PRO_0000081322"
FT DOMAIN 9..237
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT DNA_BIND 279..298
FT /note="H-T-H motif"
FT /evidence="ECO:0000255"
FT BINDING 37..44
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT BINDING 99..108
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
SQ SEQUENCE 302 AA; 33311 MW; E82D03F95436E2A1 CRC64;
MHLDEGFDDD LDEERVPNLG IVAESISQLG IDVLLSGETG TGKDTIAQRI HTISGRKGRL
VAMNCAAIPE SLAESELFGV VSPAYTGADR SRVGYIEAAQ GGTLYLDEID SMPLSLQAKL
LRVLETRALE RLGSTSTIKL DVCVIASAQS SLDDAVEQGK FRRDLYFRLN VLTLQLPPLR
TQPERILPLF KRFMAAAAKE LNVASADVCP LLQQVLLGHE WPGNIRELKA AAKRHVLGFP
VLGVDPQSEE HLACGLKSQL RAIEKALIQQ SLKRHRNCID AASLELDMPR RTLYRRIKEL
QI
