ID   HRTA_STAHJ              Reviewed;         221 AA.
AC   Q4L8L7;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Putative hemin import ATP-binding protein HrtA;
DE            EC=7.6.2.-;
GN   Name=hrtA; OrderedLocusNames=SH0699;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- FUNCTION: Part of the ABC transporter complex hrt involved in hemin
CC       import. Responsible for energy coupling to the transport system (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (HrtA),
CC       two transmembrane proteins (HrtB) and a solute-binding protein.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Peripheral membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. HrtA family.
CC       {ECO:0000305}.
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DR   EMBL; AP006716; BAE04008.1; -; Genomic_DNA.
DR   RefSeq; WP_011275024.1; NC_007168.1.
DR   AlphaFoldDB; Q4L8L7; -.
DR   SMR; Q4L8L7; -.
DR   STRING; 279808.SH0699; -.
DR   EnsemblBacteria; BAE04008; BAE04008; SH0699.
DR   GeneID; 58063112; -.
DR   KEGG; sha:SH0699; -.
DR   eggNOG; COG1136; Bacteria.
DR   HOGENOM; CLU_000604_1_22_9; -.
DR   OMA; PTRGHID; -.
DR   OrthoDB; 1181903at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   CDD; cd03255; ABC_MJ0796_LolCDE_FtsE; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017911; MacB_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding; Translocase;
KW   Transport.
FT   CHAIN           1..221
FT                   /note="Putative hemin import ATP-binding protein HrtA"
FT                   /id="PRO_0000270139"
FT   DOMAIN          3..221
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         39..46
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   221 AA;  24489 MW;  9FBAE347E76E2C60 CRC64;
     MALQLKHITK TFGNGDAQTE VLKNINFSVN QGEFIILSGA SGSGKSTLLN ILGGLLSPSS
     GDVLYKGENL FSKEVDKTSL RLNDIGFIFQ SSHLVPYLTV REQLMIVAKE AGIKRKEAKD
     KAQRLLNEIG LSHRLDVYPH LLSGGEKQRV AIMRAFMNEP KIILADEPTA SLDADRATSV
     VQMIKAHVQT KNMIGIMITH DKRLFEYADR VIEIQDGKIE L