ID   HRTB_STAAW              Reviewed;         351 AA.
AC   Q7A040;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Putative hemin transport system permease protein HrtB;
GN   Name=hrtB; OrderedLocusNames=MW2281;
OS   Staphylococcus aureus (strain MW2).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=196620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MW2;
RX   PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA   Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA   Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT   "Genome and virulence determinants of high virulence community-acquired
RT   MRSA.";
RL   Lancet 359:1819-1827(2002).
CC   -!- FUNCTION: Part of the ABC transporter complex hrt involved in hemin
CC       import. Responsible for the translocation of the substrate across the
CC       membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (HrtA),
CC       two transmembrane proteins (HrtB) and a solute-binding protein.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family. HrtB
CC       subfamily. {ECO:0000305}.
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DR   EMBL; BA000033; BAB96146.1; -; Genomic_DNA.
DR   RefSeq; WP_000761395.1; NC_003923.1.
DR   AlphaFoldDB; Q7A040; -.
DR   SMR; Q7A040; -.
DR   EnsemblBacteria; BAB96146; BAB96146; BAB96146.
DR   KEGG; sam:MW2281; -.
DR   HOGENOM; CLU_060907_1_0_9; -.
DR   OMA; KMNVQTL; -.
DR   Proteomes; UP000000418; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR003838; ABC3_permease_dom.
DR   Pfam; PF02687; FtsX; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..351
FT                   /note="Putative hemin transport system permease protein
FT                   HrtB"
FT                   /id="PRO_0000270528"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        316..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   351 AA;  39482 MW;  2409D3B9BF82ADC8 CRC64;
     MKLAIKEIMF YKFRYILITL IILLLSIMVL FISGLAQGLG RENISLFEHF DNDEYVVQKM
     KEPQIEKSQL SDTQQNQIKK VIHQEPYKMN IQTLKLSNKE QDVITMNDVK QQRIQLKKGD
     YPKNAHEVAI NDKLAADNIR VGDRLHFKNN STSYRVSGIL NDTMYAHSSI VLLNDNGFNA
     LNKVNTAFYP VKNLTQQQRD ELNKINDVQV VSEKDLTGNI ASYQAEQAPL NMMIVSLFAI
     TAIVLSAFFY VMTIQKISQI GILKAIGIKT RHLLSALVLQ ILTLTIIGVG IAVIIIVGLS
     FMMPVTMPFY LTTQNILLMV GIFILVAILG ASLSFIKLFK VDPIEAIGGA E