ID   HRTB_STAEQ              Reviewed;         350 AA.
AC   Q5HLN3;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Putative hemin transport system permease protein HrtB;
GN   Name=hrtB; OrderedLocusNames=SERP1952;
OS   Staphylococcus epidermidis (strain ATCC 35984 / RP62A).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35984 / RP62A;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- FUNCTION: Part of the ABC transporter complex hrt involved in hemin
CC       import. Responsible for the translocation of the substrate across the
CC       membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (HrtA),
CC       two transmembrane proteins (HrtB) and a solute-binding protein.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family. HrtB
CC       subfamily. {ECO:0000305}.
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DR   EMBL; CP000029; AAW52834.1; -; Genomic_DNA.
DR   RefSeq; WP_001831464.1; NC_002976.3.
DR   AlphaFoldDB; Q5HLN3; -.
DR   SMR; Q5HLN3; -.
DR   STRING; 176279.SERP1952; -.
DR   EnsemblBacteria; AAW52834; AAW52834; SERP1952.
DR   GeneID; 50017964; -.
DR   KEGG; ser:SERP1952; -.
DR   eggNOG; COG0577; Bacteria.
DR   HOGENOM; CLU_060907_1_0_9; -.
DR   OMA; KMNVQTL; -.
DR   OrthoDB; 768211at2; -.
DR   Proteomes; UP000000531; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR003838; ABC3_permease_dom.
DR   Pfam; PF02687; FtsX; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..350
FT                   /note="Putative hemin transport system permease protein
FT                   HrtB"
FT                   /id="PRO_0000270529"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        276..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        315..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   350 AA;  39168 MW;  908588AE22FB6507 CRC64;
     MNLAWKEIKF YKFRFILIMF IIFLMAIMVL FISGLAQGLA RENISIFDQI KGNQFVVQKM
     KEPQLEKSIL SRSKQDNISK IIDEKPFKMA GKTFKINGNE ENVMAINSVK NHQPNLKSGH
     YPKNGNQIAI NEKLTAEGLY LDDKVKVKGD DTTYKVVGIL KNTMYSHSNI VMMDQSKIEQ
     SSNVATFYVT NQLSKSDKNK INHIKGVQTA TTDNITSNIA SYKAEQTPLD MMIISLYIIT
     AIVLSAFFYV MTIQKTSEIG ILKAIGITTK HLLTSLILQI SMITFIGVAI AEVVILLISQ
     ILPVSMPFHI DMHNIIIVLV IFMIVGLIGT SLSFIKLIKI DPIEAIGGGQ