ID   HRTB_STAES              Reviewed;         350 AA.
AC   Q8CRA9;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Putative hemin transport system permease protein HrtB;
GN   Name=hrtB; OrderedLocusNames=SE_1940;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- FUNCTION: Part of the ABC transporter complex hrt involved in hemin
CC       import. Responsible for the translocation of the substrate across the
CC       membrane (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (HrtA),
CC       two transmembrane proteins (HrtB) and a solute-binding protein.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family. HrtB
CC       subfamily. {ECO:0000305}.
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DR   EMBL; AE015929; AAO05581.1; -; Genomic_DNA.
DR   RefSeq; NP_765495.1; NC_004461.1.
DR   RefSeq; WP_002485529.1; NZ_WBME01000017.1.
DR   AlphaFoldDB; Q8CRA9; -.
DR   SMR; Q8CRA9; -.
DR   STRING; 176280.SE_1940; -.
DR   EnsemblBacteria; AAO05581; AAO05581; SE_1940.
DR   KEGG; sep:SE_1940; -.
DR   PATRIC; fig|176280.10.peg.1893; -.
DR   eggNOG; COG0577; Bacteria.
DR   HOGENOM; CLU_060907_1_0_9; -.
DR   OMA; KMNVQTL; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR003838; ABC3_permease_dom.
DR   Pfam; PF02687; FtsX; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..350
FT                   /note="Putative hemin transport system permease protein
FT                   HrtB"
FT                   /id="PRO_0000270530"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        276..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        315..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   350 AA;  39189 MW;  C540EA0C22E591F1 CRC64;
     MNLAWKEIKF YKFRFILIMF IIFLMAIMVL FISGLAQGLA RENISIFDQI KGNQFVVQKM
     KEPQLEKSIL SRSKQDNISK IIDEKPFKMA GKTFKINGNE ENVMAINSVK NHQPNLKSGH
     YPKNGNQIAI NEKLTAEGLY LDDKVKVKGD DTTYKVVGIL KNTMYSHSNI VMMDQSKIEQ
     SSNVATFYVT NQLSKSDKNK INHIKGVQTA TTDDITSNIA SYKAEQTPLD MMIISLYIIT
     AIVLSAFFYV MTIQKTSEIG ILKAIGITTK HLLTSLILQI SMITFIGVAI AEVVIFLISQ
     ILPVSMPFHI DMHNIIIVLV VFMIVGLIGT SLSFIKLIKI DPIEAIGGGQ