HS176_ARATH
ID HS176_ARATH Reviewed; 155 AA.
AC P29830; Q8GWH1;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1993, sequence version 1.
DT 25-MAY-2022, entry version 138.
DE RecName: Full=17.6 kDa class II heat shock protein;
DE AltName: Full=17.6 kDa heat shock protein;
DE Short=AtHsp17.6;
GN Name=HSP17.6; OrderedLocusNames=At5g12020; ORFNames=F14F18.190;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Landsberg erecta; TISSUE=Leaf;
RX PubMed=1581560; DOI=10.1007/bf00019220;
RA Bartling D., Buelter H., Liebeton K., Weiler E.W.;
RT "An Arabidopsis thaliana cDNA clone encoding a 17.6 kDa class II heat shock
RT protein.";
RL Plant Mol. Biol. 18:1007-1008(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-90.
RC STRAIN=cv. Columbia; TISSUE=Dry seed;
RX PubMed=8580968; DOI=10.1046/j.1365-313x.1996.09010101.x;
RA Cooke R., Raynal M., Laudie M., Grellet F., Delseny M., Morris P.-C.,
RA Guerrier D., Giraudat J., Quigley F., Clabault G., Li Y.-F., Mache R.,
RA Krivitzky M., Gy I.J.-J., Kreis M., Lecharny A., Parmentier Y., Marbach J.,
RA Fleck J., Clement B., Philipps G., Herve C., Bardet C., Tremousaygue D.,
RA Lescure B., Lacomme C., Roby D., Jourjon M.-F., Chabrier P.,
RA Charpenteau J.-L., Desprez T., Amselem J., Chiapello H., Hoefte H.;
RT "Further progress towards a catalogue of all Arabidopsis genes: analysis of
RT a set of 5000 non-redundant ESTs.";
RL Plant J. 9:101-124(1996).
RN [7]
RP DEVELOPMENTAL STAGE, AND INDUCTION.
RX PubMed=11576425; DOI=10.1046/j.1365-313x.2001.01107.x;
RA Sun W., Bernard C., van de Cotte B., Van Montagu M., Verbruggen N.;
RT "At-HSP17.6A, encoding a small heat-shock protein in Arabidopsis, can
RT enhance osmotolerance upon overexpression.";
RL Plant J. 27:407-415(2001).
CC -!- SUBUNIT: May form oligomeric structures.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Expressed in seeds from 1 to 4 days after
CC imbibition. {ECO:0000269|PubMed:11576425}.
CC -!- INDUCTION: By heat shock. {ECO:0000269|PubMed:11576425}.
CC -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC {ECO:0000255|PROSITE-ProRule:PRU00285}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC43441.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X63443; CAA45039.1; -; mRNA.
DR EMBL; AL163812; CAB87675.1; -; Genomic_DNA.
DR EMBL; CP002688; AED91751.1; -; Genomic_DNA.
DR EMBL; AK118853; BAC43441.1; ALT_FRAME; mRNA.
DR EMBL; AY086235; AAM64311.1; -; mRNA.
DR EMBL; Z46682; CAA86670.1; -; mRNA.
DR PIR; S20871; HHMU17.
DR RefSeq; NP_196763.1; NM_121240.3.
DR AlphaFoldDB; P29830; -.
DR SMR; P29830; -.
DR STRING; 3702.AT5G12020.1; -.
DR PaxDb; P29830; -.
DR PRIDE; P29830; -.
DR ProteomicsDB; 232101; -.
DR EnsemblPlants; AT5G12020.1; AT5G12020.1; AT5G12020.
DR GeneID; 831075; -.
DR Gramene; AT5G12020.1; AT5G12020.1; AT5G12020.
DR KEGG; ath:AT5G12020; -.
DR Araport; AT5G12020; -.
DR TAIR; locus:2143109; AT5G12020.
DR eggNOG; KOG0710; Eukaryota.
DR HOGENOM; CLU_046737_5_1_1; -.
DR InParanoid; P29830; -.
DR OMA; HNEKTRN; -.
DR OrthoDB; 1187096at2759; -.
DR PhylomeDB; P29830; -.
DR PRO; PR:P29830; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; P29830; baseline and differential.
DR Genevisible; P29830; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0043621; F:protein self-association; IBA:GO_Central.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0071456; P:cellular response to hypoxia; HEP:TAIR.
DR GO; GO:0051259; P:protein complex oligomerization; IBA:GO_Central.
DR GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR GO; GO:0009408; P:response to heat; IEP:UniProtKB.
DR GO; GO:0042542; P:response to hydrogen peroxide; IBA:GO_Central.
DR GO; GO:0009651; P:response to salt stress; IBA:GO_Central.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR Pfam; PF00011; HSP20; 1.
DR SUPFAM; SSF49764; SSF49764; 1.
DR PROSITE; PS01031; SHSP; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome; Stress response.
FT CHAIN 1..155
FT /note="17.6 kDa class II heat shock protein"
FT /id="PRO_0000125991"
FT DOMAIN 38..155
FT /note="sHSP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
SQ SEQUENCE 155 AA; 17623 MW; 6590ACD7064930B9 CRC64;
MDLGRFPIIS ILEDMLEVPE DHNNEKTRNN PSRVYMRDAK AMAATPADVI EHPNAYAFVV
DMPGIKGDEI KVQVENDNVL VVSGERQREN KENEGVKYVR MERRMGKFMR KFQLPENADL
DKISAVCHDG VLKVTVQKLP PPEPKKPKTI QVQVA
