HS181_ARATH
ID HS181_ARATH Reviewed; 161 AA.
AC P19037; Q0WQZ8; Q8L8S1;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1990, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=18.1 kDa class I heat shock protein;
DE AltName: Full=18.1 kDa heat shock protein;
DE Short=AtHsp18.1;
GN Name=HSP18.1; OrderedLocusNames=At5g59720; ORFNames=MTH12.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=2482931; DOI=10.1007/bf00259608;
RA Takahashi T., Komeda Y.;
RT "Characterization of two genes encoding small heat-shock proteins in
RT Arabidopsis thaliana.";
RL Mol. Gen. Genet. 219:365-372(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP INTERACTION WITH AKR2A, AND INDUCTION BY HEAT SHOCK.
RC STRAIN=cv. Columbia;
RX PubMed=21730198; DOI=10.1104/pp.111.178681;
RA Kim D.H., Xu Z.-Y., Na Y.J., Yoo Y.-J., Lee J., Sohn E.-J., Hwang I.;
RT "Small heat shock protein Hsp17.8 functions as an AKR2A cofactor in the
RT targeting of chloroplast outer membrane proteins in Arabidopsis.";
RL Plant Physiol. 157:132-146(2011).
CC -!- SUBUNIT: May form oligomeric structures. Binds to AKR2A
CC (PubMed:21730198). {ECO:0000269|PubMed:21730198, ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- INDUCTION: Accumulates after heat shock. {ECO:0000269|PubMed:21730198}.
CC -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC {ECO:0000255|PROSITE-ProRule:PRU00285}.
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DR EMBL; X17295; CAA35183.1; -; Genomic_DNA.
DR EMBL; AB006705; BAB09509.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97223.1; -; Genomic_DNA.
DR EMBL; AY070385; AAL49881.1; -; mRNA.
DR EMBL; AY122948; AAM67481.1; -; mRNA.
DR EMBL; AK228529; BAF00451.1; -; mRNA.
DR EMBL; AY088849; AAM67156.1; -; mRNA.
DR PIR; JQ0352; JQ0352.
DR RefSeq; NP_200780.1; NM_125364.3.
DR AlphaFoldDB; P19037; -.
DR SMR; P19037; -.
DR BioGRID; 21337; 5.
DR IntAct; P19037; 3.
DR STRING; 3702.AT5G59720.1; -.
DR PaxDb; P19037; -.
DR PRIDE; P19037; -.
DR ProteomicsDB; 232104; -.
DR EnsemblPlants; AT5G59720.1; AT5G59720.1; AT5G59720.
DR GeneID; 836093; -.
DR Gramene; AT5G59720.1; AT5G59720.1; AT5G59720.
DR KEGG; ath:AT5G59720; -.
DR Araport; AT5G59720; -.
DR TAIR; locus:2174269; AT5G59720.
DR eggNOG; KOG0710; Eukaryota.
DR HOGENOM; CLU_046737_5_0_1; -.
DR InParanoid; P19037; -.
DR OMA; INDQWHR; -.
DR OrthoDB; 1187096at2759; -.
DR PhylomeDB; P19037; -.
DR PRO; PR:P19037; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; P19037; baseline and differential.
DR Genevisible; P19037; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0043621; F:protein self-association; IBA:GO_Central.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0010286; P:heat acclimation; IEP:TAIR.
DR GO; GO:0051259; P:protein complex oligomerization; IBA:GO_Central.
DR GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR GO; GO:0009408; P:response to heat; IBA:GO_Central.
DR GO; GO:0042542; P:response to hydrogen peroxide; IBA:GO_Central.
DR GO; GO:0009651; P:response to salt stress; IBA:GO_Central.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR Pfam; PF00011; HSP20; 1.
DR SUPFAM; SSF49764; SSF49764; 1.
DR PROSITE; PS01031; SHSP; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Reference proteome; Stress response.
FT CHAIN 1..161
FT /note="18.1 kDa class I heat shock protein"
FT /id="PRO_0000125972"
FT DOMAIN 45..160
FT /note="sHSP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
FT CONFLICT 23
FT /note="L -> V (in Ref. 6; AAM67156)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 161 AA; 18135 MW; BB4CA1946FBE6F6D CRC64;
MSLIPSIFGG RRSNVFDPFS QDLWDPFEGF FTPSSALANA STARDVAAFT NARVDWKETP
EAHVFKADLP GLKKEEVKVE VEDKNVLQIS GERSKENEEK NDKWHRVERA SGKFMRRFRL
PENAKMEEVK ATMENGVLTV VVPKAPEKKP QVKSIDISGA N
