HS185_ARATH
ID HS185_ARATH Reviewed; 162 AA.
AC O64564;
DT 03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=18.5 kDa class IV heat shock protein;
DE AltName: Full=18.5 kDa heat shock protein;
DE Short=AtHsp18.5;
GN Name=HSP18.5; OrderedLocusNames=At2g19310; ORFNames=F27F23.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: May form oligomeric structures.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC {ECO:0000255|PROSITE-ProRule:PRU00285, ECO:0000305}.
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DR EMBL; AC003058; AAC16461.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06867.1; -; Genomic_DNA.
DR EMBL; AF325068; AAK17136.1; -; mRNA.
DR EMBL; AY063873; AAL36229.1; -; mRNA.
DR EMBL; AY117326; AAM51401.1; -; mRNA.
DR EMBL; AY088926; AAM67232.1; -; mRNA.
DR PIR; T01279; T01279.
DR RefSeq; NP_179521.1; NM_127488.3.
DR AlphaFoldDB; O64564; -.
DR SMR; O64564; -.
DR STRING; 3702.AT2G19310.1; -.
DR PaxDb; O64564; -.
DR PRIDE; O64564; -.
DR ProteomicsDB; 232105; -.
DR EnsemblPlants; AT2G19310.1; AT2G19310.1; AT2G19310.
DR GeneID; 816448; -.
DR Gramene; AT2G19310.1; AT2G19310.1; AT2G19310.
DR KEGG; ath:AT2G19310; -.
DR Araport; AT2G19310; -.
DR TAIR; locus:2047690; AT2G19310.
DR eggNOG; KOG0710; Eukaryota.
DR HOGENOM; CLU_046737_5_0_1; -.
DR InParanoid; O64564; -.
DR OMA; QICTGDN; -.
DR OrthoDB; 1187096at2759; -.
DR PhylomeDB; O64564; -.
DR PRO; PR:O64564; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O64564; baseline and differential.
DR Genevisible; O64564; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0043621; F:protein self-association; IBA:GO_Central.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0051259; P:protein complex oligomerization; IBA:GO_Central.
DR GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR GO; GO:0009408; P:response to heat; IBA:GO_Central.
DR GO; GO:0042542; P:response to hydrogen peroxide; IBA:GO_Central.
DR GO; GO:0006979; P:response to oxidative stress; IMP:TAIR.
DR GO; GO:0009651; P:response to salt stress; IBA:GO_Central.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR SUPFAM; SSF49764; SSF49764; 1.
DR PROSITE; PS01031; SHSP; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome; Stress response.
FT CHAIN 1..162
FT /note="18.5 kDa class IV heat shock protein"
FT /id="PRO_0000387488"
FT DOMAIN 53..149
FT /note="sHSP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
SQ SEQUENCE 162 AA; 18529 MW; CC3C01F85BAC25E0 CRC64;
MSMIPISNRR RLSPGDRIWE PFELMNTFLD FPSPALFLSH HFPSLSREIF PQTSSSTVNT
QLNWTETPTA HVFKAYLPGV DQDEVIAFVD EEGYLQICTG DNKFMSRFKL PNNALTDQVT
AWMEDEFLVV FVEKDASSSP PQLPEIEENR NVRVVEITGD DD
