HS32_DICDI
ID HS32_DICDI Reviewed; 281 AA.
AC P54658; Q559F2;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=32 kDa heat shock protein;
DE AltName: Full=Protein 4-1;
GN Name=hspC; Synonyms=hsp32; ORFNames=DDB_G0272819;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], DEVELOPMENTAL STAGE, AND INDUCTION.
RX PubMed=7557471; DOI=10.1016/0378-1119(95)00407-w;
RA de Maria A.C., Gomes S.L., Juliania M.H., Mazzarella R., Klein C.;
RT "Cloning of a cDNA encoding a novel heat-shock protein from Dictyostelium
RT discoideum.";
RL Gene 163:163-164(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9256074; DOI=10.1016/s0378-1119(97)00110-8;
RA Maria A.C., Moerman A., Klein C., Gomes S.L.;
RT "Cloning, structural analysis and expression of the gene encoding Hsp32
RT from Dictyostelium discoideum.";
RL Gene 193:173-180(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- DEVELOPMENTAL STAGE: Present at high levels in growing cells but
CC decreases dramatically during the early hours of development.
CC {ECO:0000269|PubMed:7557471}.
CC -!- INDUCTION: By heat shock. {ECO:0000269|PubMed:7557471}.
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DR EMBL; L39778; AAA99510.1; -; mRNA.
DR EMBL; U40211; AAC47710.1; -; Genomic_DNA.
DR EMBL; AAFI02000008; EAL71047.1; -; Genomic_DNA.
DR PIR; JC4295; JC4295.
DR RefSeq; XP_644864.1; XM_639772.1.
DR AlphaFoldDB; P54658; -.
DR SMR; P54658; -.
DR STRING; 44689.DDB0185048; -.
DR TCDB; 1.I.1.1.5; the nuclear pore complex (npc) family.
DR PaxDb; P54658; -.
DR EnsemblProtists; EAL71047; EAL71047; DDB_G0272819.
DR GeneID; 8618543; -.
DR KEGG; ddi:DDB_G0272819; -.
DR dictyBase; DDB_G0272819; hspC.
DR eggNOG; ENOG502RH5I; Eukaryota.
DR HOGENOM; CLU_991856_0_0_1; -.
DR InParanoid; P54658; -.
DR OMA; MMQFFGT; -.
DR PRO; PR:P54658; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0000182; F:rDNA binding; IDA:dictyBase.
DR GO; GO:0034605; P:cellular response to heat; IEP:dictyBase.
DR InterPro; IPR041232; NPL.
DR Pfam; PF17800; NPL; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Stress response.
FT CHAIN 1..281
FT /note="32 kDa heat shock protein"
FT /id="PRO_0000084074"
FT REGION 142..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..168
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 281 AA; 31482 MW; 2C64F57C847D7CA4 CRC64;
MMQFFGTIVT KEEPVNLELD EGDIFHLTKA IIHPKSQGKG KVYLTAVISL MEEDEMEEDD
VDDEEESPRE DIVEIPIGIL EAGKIDQIDL NLHYNFGQIV RFELQAENGA GYVVALSGSV
ITMEQGGCDD EDCDDEHCIN HEDDEEIDSD EEFGDSDQDE EDSDDEEIPQ LIAPATKKGK
ITEISEVPES KKEKTPEPKK VPEPKKEQVK QPTQPQQKKA AAQQPEKANN KPAAASPAKP
QNNQSKNAPK QPQQQQQSPA KNNNNKRPQN QNENNKKKQK N
