ID   3SX2_MICLL              Reviewed;          79 AA.
AC   K9MCX0;
DT   29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2013, sequence version 1.
DT   25-MAY-2022, entry version 25.
DE   RecName: Full=Three-finger toxin A2 {ECO:0000305};
DE            Short=3FTx A2 {ECO:0000305};
DE   AltName: Full=Short chain alpha-neurotoxin A2 {ECO:0000303|PubMed:23438486};
DE            Short=MlatA2 {ECO:0000303|PubMed:23438486};
DE   Flags: Precursor;
OS   Micrurus laticollaris (Balsas coral snake).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Elapinae; Micrurus.
OX   NCBI_TaxID=1240351;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND SUBCELLULAR LOCATION.
RC   TISSUE=Venom, and Venom gland;
RX   PubMed=23438486; DOI=10.1016/j.toxicon.2013.02.006;
RA   Carbajal-Saucedo A., Lopez-Vera E., Benard-Valle M., Smith E.N.,
RA   Zamudio F., de Roodt A.R., Olvera-Rodriguez A.;
RT   "Isolation, characterization, cloning and expression of an alpha-neurotoxin
RT   from the venom of the Mexican coral snake Micrurus laticollaris (Squamata:
RT   Elapidae).";
RL   Toxicon 66:64-74(2013).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:23438486}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC   -!- MISCELLANEOUS: This toxin has not been detected in venom.
CC       {ECO:0000269|PubMed:23438486}.
CC   -!- SIMILARITY: Belongs to the snake three-finger toxin family. Short-chain
CC       subfamily. {ECO:0000305}.
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DR   EMBL; JQ247016; AFU76493.1; -; mRNA.
DR   AlphaFoldDB; K9MCX0; -.
DR   SMR; K9MCX0; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.10.60.10; -; 1.
DR   InterPro; IPR045860; Snake_toxin-like_sf.
DR   SUPFAM; SSF57302; SSF57302; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Secreted; Signal; Toxin.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000250|UniProtKB:Q8QGR0"
FT   CHAIN           22..79
FT                   /note="Three-finger toxin A2"
FT                   /id="PRO_0000430895"
FT   DISULFID        24..41
FT                   /evidence="ECO:0000250|UniProtKB:Q8QGR0"
FT   DISULFID        34..59
FT                   /evidence="ECO:0000250|UniProtKB:Q8QGR0"
FT   DISULFID        63..71
FT                   /evidence="ECO:0000250|UniProtKB:Q8QGR0"
FT   DISULFID        72..77
FT                   /evidence="ECO:0000250|UniProtKB:Q8QGR0"
SQ   SEQUENCE   79 AA;  8623 MW;  65B67CDECB48EFB7 CRC64;
     MKTLLLTLVV VTIVCLDLGN SLVCYVSGAW QKTCPEGQNK CEKYAVGTMH GSWIYLRGCA
     STCHEGPYNV CCSTDLCNK