AP2L1_ARATH
ID AP2L1_ARATH Reviewed; 345 AA.
AC Q94AN4; Q3EDB4; Q9S9M9;
DT 12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=AP2-like ethylene-responsive transcription factor At1g16060;
GN OrderedLocusNames=At1g16060; ORFNames=T24D18.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Probably acts as a transcriptional activator. Binds to the
CC GCC-box pathogenesis-related promoter element. May be involved in the
CC regulation of gene expression by stress factors and by components of
CC stress signal transduction pathways (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q94AN4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q94AN4-2; Sequence=VSP_026147, VSP_026148;
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. AP2
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF18503.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC010924; AAF18503.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE29405.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM58412.1; -; Genomic_DNA.
DR EMBL; AY045915; AAK76589.1; -; mRNA.
DR EMBL; AY133880; AAM91814.1; -; mRNA.
DR PIR; D86295; D86295.
DR RefSeq; NP_563990.1; NM_101474.3. [Q94AN4-1]
DR RefSeq; NP_973839.1; NM_202110.2. [Q94AN4-2]
DR AlphaFoldDB; Q94AN4; -.
DR SMR; Q94AN4; -.
DR BioGRID; 23416; 2.
DR IntAct; Q94AN4; 1.
DR STRING; 3702.AT1G16060.1; -.
DR PaxDb; Q94AN4; -.
DR PRIDE; Q94AN4; -.
DR EnsemblPlants; AT1G16060.1; AT1G16060.1; AT1G16060. [Q94AN4-1]
DR EnsemblPlants; AT1G16060.3; AT1G16060.3; AT1G16060. [Q94AN4-2]
DR GeneID; 838176; -.
DR Gramene; AT1G16060.1; AT1G16060.1; AT1G16060. [Q94AN4-1]
DR Gramene; AT1G16060.3; AT1G16060.3; AT1G16060. [Q94AN4-2]
DR KEGG; ath:AT1G16060; -.
DR Araport; AT1G16060; -.
DR TAIR; locus:2200477; AT1G16060.
DR eggNOG; ENOG502QUXV; Eukaryota.
DR HOGENOM; CLU_048809_1_1_1; -.
DR InParanoid; Q94AN4; -.
DR OMA; FINPDHE; -.
DR OrthoDB; 954522at2759; -.
DR PhylomeDB; Q94AN4; -.
DR PRO; PR:Q94AN4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q94AN4; baseline and differential.
DR Genevisible; Q94AN4; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IPI:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0010187; P:negative regulation of seed germination; IMP:TAIR.
DR GO; GO:1901959; P:positive regulation of cutin biosynthetic process; IGI:TAIR.
DR GO; GO:0045723; P:positive regulation of fatty acid biosynthetic process; IMP:TAIR.
DR GO; GO:0040008; P:regulation of growth; IMP:TAIR.
DR GO; GO:0009737; P:response to abscisic acid; IMP:TAIR.
DR GO; GO:0009651; P:response to salt stress; IMP:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IMP:TAIR.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 2.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 2.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 2.
DR SUPFAM; SSF54171; SSF54171; 2.
DR PROSITE; PS51032; AP2_ERF; 2.
PE 2: Evidence at transcript level;
KW Activator; Alternative splicing; DNA-binding; Ethylene signaling pathway;
KW Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..345
FT /note="AP2-like ethylene-responsive transcription factor
FT At1g16060"
FT /id="PRO_0000290361"
FT DNA_BIND 58..124
FT /note="AP2/ERF 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT DNA_BIND 160..218
FT /note="AP2/ERF 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 15..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 243..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..278
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..70
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_026147"
FT VAR_SEQ 71..91
FT /note="YEAHLWDKNSWNETQTKKGRQ -> MFFFLVLLTMLTGIMADSSRA (in
FT isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_026148"
SQ SEQUENCE 345 AA; 39171 MW; 4F61A70EDC1894A0 CRC64;
MFIAVEVSPV MEDITRQSKK TSVENETGDD QSATSVVLKA KRKRRSQPRD APPQRSSVHR
GVTRHRWTGR YEAHLWDKNS WNETQTKKGR QVYLGAYDEE DAAARAYDLA ALKYWGRDTI
LNFPLCNYEE DIKEMESQSK EEYIGSLRRK SSGFSRGVSK YRGVAKHHHN GRWEARIGRV
FGNKYLYLGT YATQEEAAIA YDIAAIEYRG LNAVTNFDIS RYLKLPVPEN PIDTANNLLE
SPHSDLSPFI KPNHESDLSQ SQSSSEDNDD RKTKLLKSSP LVAEEVIGPS TPPEIAPPRR
SFPEDIQTYF GCQNSGKLTA EEDDVIFGDL DSFLTPDFYS ELNDC
