3SX3_MICAT
ID 3SX3_MICAT Reviewed; 82 AA.
AC F5CPE2;
DT 26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 18.
DE RecName: Full=Three-finger toxin MALT0063C {ECO:0000312|EMBL:AED89569.1};
DE Short=3FTx MALT0063C {ECO:0000305};
DE Flags: Precursor;
OS Micrurus altirostris (Uruguayan coral snake) (Elaps altirostris).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Micrurus.
OX NCBI_TaxID=129457;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 22-36, MASS SPECTROMETRY,
RP AND SUBCELLULAR LOCATION.
RC TISSUE=Venom, and Venom gland;
RX PubMed=21515432; DOI=10.1016/j.jprot.2011.04.003;
RA Correa-Netto C., Junqueira-de-Azevedo Ide L., Silva D.A., Ho P.L.,
RA Leitao-de-Araujo M., Alves M.L., Sanz L., Foguel D., Zingali R.B.,
RA Calvete J.J.;
RT "Snake venomics and venom gland transcriptomic analysis of Brazilian coral
RT snakes, Micrurus altirostris and M. corallinus.";
RL J. Proteomics 74:1795-1809(2011).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21515432}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC -!- MASS SPECTROMETRY: Mass=6819.6; Method=Electrospray; Note=Average
CC mass.; Evidence={ECO:0000269|PubMed:21515432};
CC -!- SIMILARITY: Belongs to the snake three-finger toxin family. Short-chain
CC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JF754480; AED89569.1; -; mRNA.
DR AlphaFoldDB; F5CPE2; -.
DR SMR; F5CPE2; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.60.10; -; 1.
DR InterPro; IPR045860; Snake_toxin-like_sf.
DR SUPFAM; SSF57302; SSF57302; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Secreted; Signal; Toxin.
FT SIGNAL 1..21
FT /evidence="ECO:0000269|PubMed:21515432"
FT CHAIN 22..82
FT /note="Three-finger toxin MALT0063C"
FT /evidence="ECO:0000305|PubMed:21515432"
FT /id="PRO_0000422902"
FT DISULFID 24..42
FT /evidence="ECO:0000250|UniProtKB:P60301"
FT DISULFID 35..60
FT /evidence="ECO:0000250|UniProtKB:P60301"
FT DISULFID 64..72
FT /evidence="ECO:0000250|UniProtKB:P60301"
FT DISULFID 73..78
FT /evidence="ECO:0000250|UniProtKB:P60301"
SQ SEQUENCE 82 AA; 9083 MW; 7892D8DE9D9FCB72 CRC64;
MRTLLLTLVV VTIVCLDLGN SLICYVSEYG AKMTCPEGKT LCEKYAVPLM QGHFYFAWRC
TSTCKAGAYN ICCSTDLCNK IP