ID   HSF8_SOLLC              Reviewed;         527 AA.
AC   Q40152;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Heat shock factor protein HSF8;
DE   AltName: Full=Heat shock transcription factor 8;
DE            Short=HSTF 8;
DE   AltName: Full=Heat stress transcription factor;
GN   Name=HSF8;
OS   Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC   Solanum subgen. Lycopersicon.
OX   NCBI_TaxID=4081;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Leaf;
RA   Scharf K.D.;
RL   Submitted (JUL-1992) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DNA-binding protein that specifically binds heat shock
CC       promoter elements (HSE) and activates transcription. {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- PTM: Exhibits temperature-dependent phosphorylation. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HSF family. {ECO:0000305}.
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DR   EMBL; X67599; CAA47868.1; -; Genomic_DNA.
DR   PIR; S25478; S25478.
DR   RefSeq; NP_001296177.1; NM_001309248.1.
DR   AlphaFoldDB; Q40152; -.
DR   SMR; Q40152; -.
DR   STRING; 4081.Solyc08g005170.2.1; -.
DR   PaxDb; Q40152; -.
DR   PRIDE; Q40152; -.
DR   EnsemblPlants; Solyc08g005170.3.1; Solyc08g005170.3.1; Solyc08g005170.3.
DR   GeneID; 101263626; -.
DR   Gramene; Solyc08g005170.3.1; Solyc08g005170.3.1; Solyc08g005170.3.
DR   KEGG; sly:101263626; -.
DR   eggNOG; KOG0627; Eukaryota.
DR   HOGENOM; CLU_030308_0_4_1; -.
DR   InParanoid; Q40152; -.
DR   OMA; MGATNIK; -.
DR   OrthoDB; 1154048at2759; -.
DR   PhylomeDB; Q40152; -.
DR   Proteomes; UP000004994; Chromosome 8.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0034605; P:cellular response to heat; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000232; HSF_DNA-bd.
DR   InterPro; IPR027725; HSF_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10015; PTHR10015; 1.
DR   Pfam; PF00447; HSF_DNA-bind; 1.
DR   PRINTS; PR00056; HSFDOMAIN.
DR   SMART; SM00415; HSF; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS00434; HSF_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nucleus; Phosphoprotein; Reference proteome;
KW   Stress response; Transcription; Transcription regulation.
FT   CHAIN           1..527
FT                   /note="Heat shock factor protein HSF8"
FT                   /id="PRO_0000124591"
FT   DNA_BIND        39..133
FT                   /evidence="ECO:0000250"
FT   REGION          128..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          241..273
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          297..341
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..155
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        246..261
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..341
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   527 AA;  57701 MW;  357EC1605C6C0C0E CRC64;
     MEPNSYGSGK AAVGDGVGAP MLQTAPAPAP IPSANAPPPF LVKTYDMVDD PSTDKIVSWS
     PTNNSFVVWD PPEFAKDLLP KYFKHNNFSS FVRQLNTYGF RKVDPDRWEF ANEGFLRGQK
     HLLKSISRRK PAHGHAQQQQ QPHGNAQQQM QPPGHSASVG ACVEVGKFGL EEEVERLKRD
     KNVLMQELVR LRQQQQATDN QLQGMVQRLQ GMELRQQQMM SFLAKAVNRP GFLAQFVQQQ
     NESNKRIAEG SKKRRIKQDI ESQDPSVTPA DGQIVKYQPG INEAAKAMLR ELSKLDSSPR
     LDNFSNSPES FLIGDGSPQS NASSGRVSGV TLQEVPPTSG KPLLNTASAI AGQSLLPATS
     EMQSSHLGTC SEIINNQLSN IIPLVGGEDL HPGSLSASDM IMPELSQLQG ILPENNTDVI
     GCDSFMDTSA VEGKVGLDII GSCLSPGADI DWQSGLLDEI EEFPSVGDPF WEKFLQSPCS
     PDAAMDDDIS NTSETKPQIN GWDKTQNMEH LTEQMGATNI KQQKHMI