ID   HSFA3_ORYSJ             Reviewed;         498 AA.
AC   Q6H6Q7; B7ESF3;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Heat stress transcription factor A-3;
DE   AltName: Full=Heat stress transcription factor 7;
DE            Short=OsHsf-07;
GN   Name=HSFA3; Synonyms=HSF07; OrderedLocusNames=Os02g0527300, LOC_Os02g32590;
GN   ORFNames=P0458B05.23, P0475F05.3;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=15625403; DOI=10.1007/bf02712120;
RA   Baniwal S.K., Bharti K., Chan K.Y., Fauth M., Ganguli A., Kotak S.,
RA   Mishra S.K., Nover L., Port M., Scharf K.-D., Tripp J., Weber C.,
RA   Zielinski D., von Koskull-Doering P.;
RT   "Heat stress response in plants: a complex game with chaperones and more
RT   than twenty heat stress transcription factors.";
RL   J. Biosci. 29:471-487(2004).
RN   [6]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18407058; DOI=10.1016/s1673-8527(08)60016-8;
RA   Guo J., Wu J., Ji Q., Wang C., Luo L., Yuan Y., Wang Y., Wang J.;
RT   "Genome-wide analysis of heat shock transcription factor families in rice
RT   and Arabidopsis.";
RL   J. Genet. Genomics 35:105-118(2008).
CC   -!- FUNCTION: Transcriptional regulator that specifically binds DNA of heat
CC       shock promoter elements (HSE). {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
CC   -!- DOMAIN: The hydrophobic-rich region (HR-A/B) corresponds to the
CC       oligomerization domain.
CC   -!- PTM: Exhibits temperature-dependent phosphorylation. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HSF family. Class A subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AP004777; BAD25410.1; -; Genomic_DNA.
DR   EMBL; AP004879; BAD25592.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF08917.1; -; Genomic_DNA.
DR   EMBL; AP014958; BAS78998.1; -; Genomic_DNA.
DR   EMBL; AK101934; BAG95300.1; -; mRNA.
DR   RefSeq; XP_015623061.1; XM_015767575.1.
DR   AlphaFoldDB; Q6H6Q7; -.
DR   SMR; Q6H6Q7; -.
DR   STRING; 4530.OS02T0527300-01; -.
DR   PaxDb; Q6H6Q7; -.
DR   PRIDE; Q6H6Q7; -.
DR   EnsemblPlants; Os02t0527300-01; Os02t0527300-01; Os02g0527300.
DR   GeneID; 4329526; -.
DR   Gramene; Os02t0527300-01; Os02t0527300-01; Os02g0527300.
DR   KEGG; osa:4329526; -.
DR   eggNOG; KOG0627; Eukaryota.
DR   HOGENOM; CLU_030308_9_0_1; -.
DR   InParanoid; Q6H6Q7; -.
DR   OMA; VWDPSTF; -.
DR   OrthoDB; 1154048at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q6H6Q7; OS.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0034605; P:cellular response to heat; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000232; HSF_DNA-bd.
DR   InterPro; IPR027725; HSF_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10015; PTHR10015; 1.
DR   Pfam; PF00447; HSF_DNA-bind; 1.
DR   PRINTS; PR00056; HSFDOMAIN.
DR   SMART; SM00415; HSF; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS00434; HSF_DOMAIN; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; DNA-binding; Nucleus; Phosphoprotein;
KW   Reference proteome; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..498
FT                   /note="Heat stress transcription factor A-3"
FT                   /id="PRO_0000350826"
FT   REGION          156..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          184..234
FT                   /note="Hydrophobic repeat HR-A/B"
FT   REGION          263..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          356..382
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          180..235
FT                   /evidence="ECO:0000255"
FT   MOTIF           258..263
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   MOTIF           309..316
FT                   /note="Nuclear export signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        157..178
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..291
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   498 AA;  55099 MW;  A44DCBF21DAE36BD CRC64;
     MDHNTDPPPT TMVDAAAALL LEPKLEGYDD DGGGEPLQPA PFVSPLDQLM QPPRPLEALL
     QGPQLPPFLS KTYDLVCEPE LDGVISWGHA GNSFVVWDPS AFARDVLPHH FKHNNFSSFV
     RQLNTYGFRK VHADRWEFAH EDFLRHSKHL LKKIVRRRSS PTQQSGLQPG SSGESGLDPE
     LNTLRREKSA LLQEVTRLKQ EHLQTIEQMS TLNQRLESAE DRQKQMVSFL AKLLQNPTFL
     RQLKMHRQQK EIDSTRVKRK FLKHVPHGNI DSGESSSQHT GESNLDFSPT SLDLPATHSD
     ILDLQNFLLE DGDLNLAMLP ENIGLDGIEA PDDIGALVQG FDTQEELELG SGVELLEIPP
     ASGPRGQDPT IGRSKGKNVL SPGLDATSSE ADCLGSFSDN MGMLSDSMLQ TAGKLMDADD
     DERIWGVDAS SALQSSCSGT SQQAYGSLVS DPYLMEMANK PEKFWELDFQ ALDDGDLQLD
     KCVIDDPALQ QQRGNMNS