ID   HSL33_DICDI             Reviewed;          98 AA.
AC   P15648; Q54UR5;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=HssA/B-like protein 33;
DE   AltName: Full=Protein 2C;
GN   Name=hssl33; Synonyms=2C; ORFNames=DDB_G0280847;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=AX2;
RX   PubMed=2157129; DOI=10.1111/j.1365-2958.1990.tb02022.x;
RA   Ramji D.P., Richards A.J., Jagger P., Bleasby A., Hames B.D.;
RT   "Two cyclic AMP-regulated genes from Dictyostelium discoideum encode
RT   homologous proteins.";
RL   Mol. Microbiol. 4:129-135(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AX4;
RX   PubMed=15010511; DOI=10.1093/nar/gkh262;
RA   Urushihara H., Morio T., Saito T., Kohara Y., Koriki E., Ochiai H.,
RA   Maeda M., Williams J.G., Takeuchi I., Tanaka Y.;
RT   "Analyses of cDNAs from growth and slug stages of Dictyostelium
RT   discoideum.";
RL   Nucleic Acids Res. 32:1647-1653(2004).
RN   [4]
RP   DEVELOPMENTAL STAGE.
RX   PubMed=2161991; DOI=10.1111/j.1365-2958.1990.tb00630.x;
RA   Corney A.J., Richards A.J., Phillpots T., Hames B.D.;
RT   "Developmental regulation of cell-type-enriched mRNAs in Dictyostelium
RT   discoideum.";
RL   Mol. Microbiol. 4:613-623(1990).
RN   [5]
RP   DEVELOPMENTAL STAGE.
RX   PubMed=2177818; DOI=10.1111/j.1365-2958.1990.tb00707.x;
RA   Richards A.J., Corney A.J., Hames B.D.;
RT   "Cell-type-specific genes expressed late in Dictyostelium development show
RT   markedly different responses to 3'5' cyclic AMP.";
RL   Mol. Microbiol. 4:1279-1291(1990).
CC   -!- DEVELOPMENTAL STAGE: Expressed in the prestalk cells and prespore
CC       cells. Expressed only late in development. First detected in the finger
CC       stage and expression levels peak in late culmination (18-22 hours). Its
CC       expression ceases upon cell disaggregation but is fully restored by
CC       exogenous cAMP after a 5 hour delay. {ECO:0000269|PubMed:2161991,
CC       ECO:0000269|PubMed:2177818}.
CC   -!- SIMILARITY: Belongs to the hssA/B family. {ECO:0000305}.
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DR   EMBL; X16827; CAA34727.1; -; mRNA.
DR   EMBL; AAFI02000039; EAL66965.1; -; Genomic_DNA.
DR   EMBL; AU037627; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AU060838; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; BJ371106; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; BJ397827; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; S08137; S08137.
DR   RefSeq; XP_640956.1; XM_635864.1.
DR   AlphaFoldDB; P15648; -.
DR   PaxDb; P15648; -.
DR   EnsemblProtists; EAL66965; EAL66965; DDB_G0280847.
DR   GeneID; 8622760; -.
DR   KEGG; ddi:DDB_G0280847; -.
DR   dictyBase; DDB_G0280847; 2C.
DR   HOGENOM; CLU_181850_0_0_1; -.
DR   PRO; PR:P15648; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0031154; P:culmination involved in sorocarp development; IEP:UniProtKB.
DR   GO; GO:0031153; P:slug development involved in sorocarp development; IEP:UniProtKB.
DR   InterPro; IPR008455; HssA/B-related.
DR   Pfam; PF05710; Coiled; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..98
FT                   /note="HssA/B-like protein 33"
FT                   /id="PRO_0000064359"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          60..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   98 AA;  8836 MW;  BD7BFDF649EB1D50 CRC64;
     MTLFSSISSM SSSMTSSRSS FSSFGSGTSM GSNSIACSVG SGGGGCGSGS GGCGDLTGGA
     KSSGGSCGGK GGPHNHGHGN GHGPHGHGGK GSGGSCSC