ID   HSLR_HAEIN              Reviewed;         131 AA.
AC   P44754;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Heat shock protein 15 homolog;
DE            Short=HSP15;
GN   Name=hslR; OrderedLocusNames=HI_0562;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Involved in the recycling of free 50S ribosomal subunits that
CC       still carry a nascent chain. Binds RNA more specifically than DNA.
CC       Binds with very high affinity to the free 50S ribosomal subunit. Does
CC       not bind it when it is part of the 70S ribosome (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HSP15 family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22220.1; -; Genomic_DNA.
DR   PIR; F64154; F64154.
DR   RefSeq; NP_438719.1; NC_000907.1.
DR   RefSeq; WP_005654696.1; NC_000907.1.
DR   AlphaFoldDB; P44754; -.
DR   SMR; P44754; -.
DR   STRING; 71421.HI_0562; -.
DR   EnsemblBacteria; AAC22220; AAC22220; HI_0562.
DR   KEGG; hin:HI_0562; -.
DR   PATRIC; fig|71421.8.peg.582; -.
DR   eggNOG; COG1188; Bacteria.
DR   HOGENOM; CLU_101003_2_1_6; -.
DR   OMA; IDKYLWC; -.
DR   PhylomeDB; P44754; -.
DR   BioCyc; HINF71421:G1GJ1-574-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0043023; F:ribosomal large subunit binding; IEA:InterPro.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:InterPro.
DR   GO; GO:0034605; P:cellular response to heat; IEA:InterPro.
DR   CDD; cd00165; S4; 1.
DR   Gene3D; 3.10.290.10; -; 1.
DR   InterPro; IPR025708; HSP15.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   Pfam; PF01479; S4; 1.
DR   PIRSF; PIRSF016821; HSP15; 1.
DR   SMART; SM00363; S4; 1.
DR   PROSITE; PS50889; S4; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; RNA-binding.
FT   CHAIN           1..131
FT                   /note="Heat shock protein 15 homolog"
FT                   /id="PRO_0000201744"
FT   DOMAIN          6..67
FT                   /note="S4 RNA-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00182"
FT   REGION          98..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..131
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   131 AA;  15505 MW;  881BB444C3ABD776 CRC64;
     MAEKEVRLDK WLWAARFYKT RSIAKAMIES GKVHYNNQRA KVSKIVEVGA MLKLRQGNEE
     KEIKIIALSD QRRGAPEAQL LYQETESSVK KREEIAWARK NNSLSMPHPD RRPNKKERRD
     LLKFKHQDKF E