ID   AP4AT_XENLA             Reviewed;         559 AA.
AC   Q4V832;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 2.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=AP-4 complex accessory subunit tepsin {ECO:0000305};
DE   AltName: Full=Tetra-epsin {ECO:0000250|UniProtKB:Q96N21};
GN   Name=tepsin {ECO:0000250|UniProtKB:Q96N21};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in vesicular trafficking of proteins at the
CC       trans-Golgi network. {ECO:0000250|UniProtKB:Q96N21}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane
CC       {ECO:0000250|UniProtKB:Q96N21}; Peripheral membrane protein
CC       {ECO:0000250|UniProtKB:Q96N21}. Cytoplasmic vesicle
CC       {ECO:0000250|UniProtKB:Q96N21}. Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:Q96N21}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH97570.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; BC097570; AAH97570.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; Q4V832; -.
DR   SMR; Q4V832; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0030662; C:coated vesicle membrane; ISS:UniProtKB.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   CDD; cd03572; ENTH_like_Tepsin; 1.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR035802; ENTH/VHS_tepsin.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR039273; TEPSIN.
DR   PANTHER; PTHR21514; PTHR21514; 1.
DR   Pfam; PF01417; ENTH; 1.
DR   SUPFAM; SSF48464; SSF48464; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Cytoplasmic vesicle; Golgi apparatus; Membrane;
KW   Reference proteome.
FT   CHAIN           1..559
FT                   /note="AP-4 complex accessory subunit tepsin"
FT                   /id="PRO_0000286680"
FT   DOMAIN          2..135
FT                   /note="ENTH"
FT   REGION          131..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          214..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          472..491
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        131..152
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        248..286
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   559 AA;  60398 MW;  2FA5245591883952 CRC64;
     MLDRLAFLQQ LPLLLKGTSD DDTPCPGYLY EEFAKISYES VGSCQCLLEY LLNRLQTSSC
     HVKLKVLKIL LSLCFHGSPQ FIQDLRRNSA YIQEAAAVSG PPDPLHGISL YQKVRVTAQE
     IVGNLFSESI PSPSHTVSAK ERSQSGMGSQ ASSAPALHGF GYSQEEKNLG NSKDTFLNGI
     QRAAVAVTHS VLPGAGLSHT HACERADDAY KPVAIPSTDR RPLPGNSLPT SAHRGCHRSG
     VPGGGWDESD SGNSSQESPH DKSPLSRSSD VGSKSGSDGQ SRNSQRESLD ITDRVEFTHL
     SDCQQEARLV QEVTWGKRVF LTQEESQQFV RGCSLLNCEV VFEMLNCSLT DDSNCIKLRS
     MCAISSLMAS DLLSHEHMLA VVRQNLQTLT GGPPGPVKDK ATKILRQFQA LTQNFSERGA
     VHHETSPSPT THCSLDLFAD VIPHSVVSGL LTSLSVPSSP TLNVQNTVCS LPNGAANQKN
     PNGSTEKSDP AEELRVETGD HISTNIHVSL FEGMELVGTM KCSHKEDTIG YRAGGLSVEP
     AKEEPSKPTL SSVFSFLNT