ID   3SX6_OXYMI              Reviewed;          81 AA.
AC   A7X4T2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Three-finger toxin 3FTx-Oxy6 {ECO:0000312|EMBL:ABU68554.1};
DE   Flags: Precursor;
OS   Oxyuranus microlepidotus (Inland taipan) (Diemenia microlepidota).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Acanthophiinae; Oxyuranus.
OX   NCBI_TaxID=111177;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=17855442; DOI=10.1074/mcp.m700094-mcp200;
RA   Fry B.G., Scheib H., van der Weerd L., Young B., McNaughtan J.,
RA   Ramjan S.F.R., Vidal N., Poelmann R.E., Norman J.A.;
RT   "Evolution of an arsenal: structural and functional diversification of the
RT   venom system in the advanced snakes (Caenophidia).";
RL   Mol. Cell. Proteomics 7:215-246(2008).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the snake three-finger toxin family. Short-chain
CC       subfamily. {ECO:0000305}.
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DR   EMBL; EU029754; ABU68554.1; -; mRNA.
DR   AlphaFoldDB; A7X4T2; -.
DR   SMR; A7X4T2; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   CDD; cd00206; snake_toxin; 1.
DR   Gene3D; 2.10.60.10; -; 1.
DR   InterPro; IPR003571; Snake_3FTx.
DR   InterPro; IPR045860; Snake_toxin-like_sf.
DR   InterPro; IPR035076; Toxin/TOLIP.
DR   Pfam; PF00087; Toxin_TOLIP; 1.
DR   SUPFAM; SSF57302; SSF57302; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Secreted; Signal; Toxin.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..81
FT                   /note="Three-finger toxin 3FTx-Oxy6"
FT                   /id="PRO_0000316178"
FT   DISULFID        24..43
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
FT   DISULFID        36..61
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
FT   DISULFID        65..73
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
FT   DISULFID        74..79
FT                   /evidence="ECO:0000250|UniProtKB:P60301"
SQ   SEQUENCE   81 AA;  9239 MW;  1253EA6969189E55 CRC64;
     MKTLLLSLVV MTIVYLDLGY TLKCHESENL DDHVVCEEDE TMCYKFTFVP FRDFEIVARG
     CSASCPEEKD VVCCSTDLCN K