HSP16_CAEEL
ID HSP16_CAEEL Reviewed; 143 AA.
AC P06581; P02514;
DT 01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1988, sequence version 1.
DT 03-AUG-2022, entry version 143.
DE RecName: Full=Heat shock protein Hsp-16.41;
GN Name=hsp-16.41; Synonyms=hsp16-41; ORFNames=Y46H3A.2;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3017958; DOI=10.1016/s0021-9258(18)67194-7;
RA Jones D., Russnak R.H., Kay R.J., Candido E.P.M.;
RT "Structure, expression, and evolution of a heat shock gene locus in
RT Caenorhabditis elegans that is flanked by repetitive elements.";
RL J. Biol. Chem. 261:12006-12015(1986).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 47-143.
RX PubMed=6190129; DOI=10.1093/nar/11.10.3187;
RA Russnak R.H., Jones D., Candido E.P.M.;
RT "Cloning and analysis of cDNA sequences coding for two 16 kilodalton heat
RT shock proteins (hsps) in Caenorhabditis elegans: homology with the small
RT hsps of Drosophila.";
RL Nucleic Acids Res. 11:3187-3205(1983).
CC -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC {ECO:0000255|PROSITE-ProRule:PRU00285}.
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DR EMBL; M14334; AAA28070.1; ALT_SEQ; Genomic_DNA.
DR EMBL; FO081307; CCD70650.1; -; Genomic_DNA.
DR EMBL; X01577; CAA25732.1; -; mRNA.
DR PIR; A25199; HHKW41.
DR RefSeq; NP_872116.2; NM_182316.4.
DR AlphaFoldDB; P06581; -.
DR SMR; P06581; -.
DR BioGRID; 43725; 1.
DR IntAct; P06581; 2.
DR STRING; 6239.Y46H3A.2; -.
DR EPD; P06581; -.
DR PaxDb; P06581; -.
DR PeptideAtlas; P06581; -.
DR EnsemblMetazoa; Y46H3A.2.1; Y46H3A.2.1; WBGene00002018.
DR GeneID; 178660; -.
DR KEGG; cel:CELE_Y46H3A.2; -.
DR UCSC; Y46H3A.2; c. elegans.
DR CTD; 178660; -.
DR WormBase; Y46H3A.2; CE22003; WBGene00002018; hsp-16.41.
DR eggNOG; KOG3591; Eukaryota.
DR GeneTree; ENSGT00970000196196; -.
DR HOGENOM; CLU_095001_4_1_1; -.
DR InParanoid; P06581; -.
DR OMA; LMNRMMY; -.
DR OrthoDB; 1187096at2759; -.
DR PhylomeDB; P06581; -.
DR Reactome; R-CEL-3371571; HSF1-dependent transactivation.
DR PRO; PR:P06581; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00002018; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR GO; GO:0051082; F:unfolded protein binding; ISS:WormBase.
DR GO; GO:0050829; P:defense response to Gram-negative bacterium; IEP:WormBase.
DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; HEP:WormBase.
DR GO; GO:0042026; P:protein refolding; IBA:GO_Central.
DR GO; GO:0009408; P:response to heat; IEP:WormBase.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR InterPro; IPR001436; Alpha-crystallin/sHSP_animal.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR PANTHER; PTHR45640; PTHR45640; 1.
DR Pfam; PF00011; HSP20; 1.
DR PRINTS; PR00299; ACRYSTALLIN.
DR SUPFAM; SSF49764; SSF49764; 1.
DR PROSITE; PS01031; SHSP; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Stress response.
FT CHAIN 1..143
FT /note="Heat shock protein Hsp-16.41"
FT /id="PRO_0000125960"
FT DOMAIN 35..140
FT /note="sHSP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
SQ SEQUENCE 143 AA; 16252 MW; C1D0F59D26E36C24 CRC64;
MLMLRSPYSD SNALDHFLDE LTGSVQFPYW RNADHNSFNF SDNIGEIVND ESKFSVQLDV
SHFKPENLKI KLDGRELKIE GIQETKSEHG YLKRSFSKMI LLPEDADLPS VKSAISNEGK
LQIEAPKKTN SSRSIPINFV AKH
