位置:首页 > 蛋白库 > HSP1_ALLMI
HSP1_ALLMI
ID   HSP1_ALLMI              Reviewed;          57 AA.
AC   Q7LZB6;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 44.
DE   RecName: Full=Sperm protamine P1-type;
DE   AltName: Full=Protamine II;
OS   Alligator mississippiensis (American alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=8496;
RN   [1]
RP   PROTEIN SEQUENCE OF 2-57.
RC   TISSUE=Sperm;
RX   PubMed=8798564; DOI=10.1074/jbc.271.38.23547;
RA   Hunt J.G., Kasinsky H.E., Elsey R.M., Wright C.L., Rice P., Bell J.E.,
RA   Sharp D.J., Kiss A.J., Hunt D.F., Arnott D.P., Russ M.M., Shabanowitz J.,
RA   Ausio J.;
RT   "Protamines of reptiles.";
RL   J. Biol. Chem. 271:23547-23557(1996).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; C58213; C58213.
DR   AlphaFoldDB; Q7LZB6; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR   InterPro; IPR000221; Protamine_P1.
DR   PROSITE; PS00048; PROTAMINE_P1; 1.
PE   1: Evidence at protein level;
KW   Chromosome; Developmental protein; Differentiation;
KW   Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW   Nucleus; Spermatogenesis.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:8798564"
FT   CHAIN           2..57
FT                   /note="Sperm protamine P1-type"
FT                   /id="PRO_0000191591"
FT   REGION          1..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   57 AA;  7669 MW;  2894208FCFAFB9F7 CRC64;
     MARYRHNRSR SRSRHRRRRR GHRGGRYRRR RRRGRYGHRR HHRGHSRRRR KRRRSRH
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024