ID   HSP1_ANTST              Reviewed;          63 AA.
AC   P42129; Q71V21;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Sperm protamine P1;
GN   Name=PRM1;
OS   Antechinus stuartii (Brown marsupial mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Dasyuromorphia; Dasyuridae; Antechinus.
OX   NCBI_TaxID=9283;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Sperm;
RX   PubMed=7700877; DOI=10.1098/rspb.1995.0002;
RA   Retief J.D., Krajewski C., Westerman M., Winkfein R.J., Dixon G.H.;
RT   "Molecular phylogeny and evolution of marsupial protamine P1 genes.";
RL   Proc. R. Soc. B 259:7-14(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Armstrong L.A., Krajewski C., Westerman M.;
RT   "Phylogeny of the dasyurid marsupial genus Antechinus based on cytochrome-
RT   b, 12S-rRNA, and protamine-P1 genes.";
RL   J. Mammal. 79:1379-1389(1998).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L35335; AAB95428.1; -; Genomic_DNA.
DR   EMBL; AF038292; AAC15619.1; -; Genomic_DNA.
DR   AlphaFoldDB; P42129; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR   InterPro; IPR000221; Protamine_P1.
DR   PROSITE; PS00048; PROTAMINE_P1; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT   CHAIN           1..63
FT                   /note="Sperm protamine P1"
FT                   /id="PRO_0000191448"
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        23
FT                   /note="R -> RR (in Ref. 1; AAB95428)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   63 AA;  8697 MW;  99A6BEA7CBB77964 CRC64;
     MARYRRHSRS RSRSRYRRRR RRRSRHHNRR RTYRRSRRHS RRRRGRRRGY SRRRYSRRGR
     RRY