HSP1_CHRPI
ID HSP1_CHRPI Reviewed; 59 AA.
AC Q7LZB2;
DT 10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 43.
DE RecName: Full=Sperm protamine P1-type;
DE AltName: Full=Protamine I-1;
OS Chrysemys picta bellii (Western painted turtle) (Emys bellii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Testudinoidea; Emydidae; Chrysemys.
OX NCBI_TaxID=8478;
RN [1]
RP PROTEIN SEQUENCE OF 2-59.
RC TISSUE=Sperm;
RX PubMed=8798564; DOI=10.1074/jbc.271.38.23547;
RA Hunt J.G., Kasinsky H.E., Elsey R.M., Wright C.L., Rice P., Bell J.E.,
RA Sharp D.J., Kiss A.J., Hunt D.F., Arnott D.P., Russ M.M., Shabanowitz J.,
RA Ausio J.;
RT "Protamines of reptiles.";
RL J. Biol. Chem. 271:23547-23557(1996).
CC -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC during the haploid phase of spermatogenesis. They compact sperm DNA
CC into a highly condensed, stable and inactive complex (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Testis.
CC -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR PIR; A58208; A58208.
DR AlphaFoldDB; Q7LZB2; -.
DR Proteomes; UP000694380; Unplaced.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR InterPro; IPR000221; Protamine_P1.
DR PROSITE; PS00048; PROTAMINE_P1; 1.
PE 1: Evidence at protein level;
KW Chromosome; Developmental protein; Differentiation;
KW Direct protein sequencing; DNA condensation; DNA-binding; Nucleosome core;
KW Nucleus; Reference proteome; Spermatogenesis.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:8798564"
FT CHAIN 2..59
FT /note="Sperm protamine P1-type"
FT /id="PRO_0000191592"
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 59 AA; 7751 MW; 3826B9CA5A246924 CRC64;
MARYRRNRSR SRSRRRRRRR GGRGGRRGRR RRRHGQRRRG RRGRERTRRR RRRRRRSSS