ID   HSP1_DASVI              Reviewed;          62 AA.
AC   P67835; P42133; P42135; Q71VG6;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=Sperm protamine P1;
GN   Name=PRM1;
OS   Dasyurus viverrinus (Eastern quoll) (Didelphis viverrina).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Dasyuromorphia; Dasyuridae; Dasyurus.
OX   NCBI_TaxID=9279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Sperm;
RX   PubMed=7700877; DOI=10.1098/rspb.1995.0002;
RA   Retief J.D., Krajewski C., Westerman M., Winkfein R.J., Dixon G.H.;
RT   "Molecular phylogeny and evolution of marsupial protamine P1 genes.";
RL   Proc. R. Soc. B 259:7-14(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Krajewski C., Young J., Buckley L., Woolley P.A., Westerman M.;
RT   "Reconstructing the taxonomic radiation of dasyurine marsupials with
RT   cytochrome b, 12S rRNA, and protamine P1 gene trees.";
RL   J. Mammal. Evol. 4:217-236(1997).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L35340; AAA74599.1; -; Genomic_DNA.
DR   EMBL; AF010273; AAB69303.1; -; Genomic_DNA.
DR   AlphaFoldDB; P67835; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR   InterPro; IPR000221; Protamine_P1.
DR   PROSITE; PS00048; PROTAMINE_P1; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT   CHAIN           1..62
FT                   /note="Sperm protamine P1"
FT                   /id="PRO_0000191467"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        7
FT                   /note="H -> R (in Ref. 1; AAA74599)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        62
FT                   /note="Missing (in Ref. 1; AAA74599)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   62 AA;  8522 MW;  86B7B72785AA5F21 CRC64;
     MARYRRHSRS RSRSRYRRRR RRRSRGRRRR TYRRSRRHSR RRRGRRRGYS RRRYSRRGRR
     RY