ID   HSP1_EPTFU              Reviewed;          48 AA.
AC   Q7JH05;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 40.
DE   RecName: Full=Sperm protamine P1;
GN   Name=PRM1;
OS   Eptesicus fuscus (Big brown bat) (Vespertilio fuscus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC   Eptesicus.
OX   NCBI_TaxID=29078;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11884158; DOI=10.1006/mpev.2001.1051;
RA   Van Den Bussche R.A., Hoofer S.R., Hansen E.W.;
RT   "Characterization and phylogenetic utility of the mammalian protamine P1
RT   gene.";
RL   Mol. Phylogenet. Evol. 22:333-341(2002).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF435942; AAL35576.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q7JH05; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR   InterPro; IPR000221; Protamine_P1.
DR   Pfam; PF00260; Protamine_P1; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT   CHAIN           1..48
FT                   /note="Sperm protamine P1"
FT                   /id="PRO_0000191477"
SQ   SEQUENCE   48 AA;  6598 MW;  D10C0AE2D2CE295B CRC64;
     MARYRCCRSR SRCRRRRRRC YRRRRRCCRR RRRRVCCRRY TVIRCRRR