ID   HSP1_GALVR              Reviewed;          47 AA.
AC   Q8WP00;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Sperm protamine P1;
GN   Name=PRM1;
OS   Galeopterus variegatus (Malayan flying lemur) (Cynocephalus variegatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Dermoptera; Cynocephalidae; Galeopterus.
OX   NCBI_TaxID=482537;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11884158; DOI=10.1006/mpev.2001.1051;
RA   Van Den Bussche R.A., Hoofer S.R., Hansen E.W.;
RT   "Characterization and phylogenetic utility of the mammalian protamine P1
RT   gene.";
RL   Mol. Phylogenet. Evol. 22:333-341(2002).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
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DR   EMBL; AF435927; AAL35561.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8WP00; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT   CHAIN           1..47
FT                   /note="Sperm protamine P1"
FT                   /id="PRO_0000191458"
SQ   SEQUENCE   47 AA;  6372 MW;  076776D4BFDFC523 CRC64;
     MARYRCCRSR SRCRRRRRSC RRRRRCRRRR ARRSCRRRYS LRCCRRY