ID   HSP1_MACMU              Reviewed;          51 AA.
AC   Q9GJU4;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Sperm protamine P1;
GN   Name=PRM1;
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Karanth P.K., Stewart C.-B., Holt R.A., de Koning J., Messier W.;
RT   "Positive Darwinian selection on the lineage leading to humans.";
RL   Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
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DR   EMBL; AF119240; AAG42164.1; -; Genomic_DNA.
DR   RefSeq; NP_001137294.1; NM_001143822.1.
DR   AlphaFoldDB; Q9GJU4; -.
DR   Ensembl; ENSMMUT00000082005; ENSMMUP00000062948; ENSMMUG00000049384.
DR   GeneID; 716327; -.
DR   KEGG; mcc:716327; -.
DR   CTD; 5619; -.
DR   VEuPathDB; HostDB:ENSMMUG00000049384; -.
DR   GeneTree; ENSGT00950000183635; -.
DR   HOGENOM; CLU_214580_2_0_1; -.
DR   OMA; MARYICC; -.
DR   Proteomes; UP000006718; Chromosome 20.
DR   Bgee; ENSMMUG00000049384; Expressed in testis and 15 other tissues.
DR   ExpressionAtlas; Q9GJU4; baseline.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR   InterPro; IPR000221; Protamine_P1.
DR   Pfam; PF00260; Protamine_P1; 1.
DR   PROSITE; PS00048; PROTAMINE_P1; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Reference proteome; Spermatogenesis.
FT   CHAIN           1..51
FT                   /note="Sperm protamine P1"
FT                   /id="PRO_0000191491"
SQ   SEQUENCE   51 AA;  6943 MW;  3CC3CDB2BF3BB815 CRC64;
     MARYRCCRSQ SRSRCCRRRR RCRRRRRRRC RARRRAMRCC RRRYRLRCRR Y