ID   HSP1_MONDO              Reviewed;          58 AA.
AC   P67836; P35305;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Sperm protamine P1;
GN   Name=PRM1;
OS   Monodelphis domestica (Gray short-tailed opossum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX   NCBI_TaxID=13616;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7700877; DOI=10.1098/rspb.1995.0002;
RA   Retief J.D., Krajewski C., Westerman M., Winkfein R.J., Dixon G.H.;
RT   "Molecular phylogeny and evolution of marsupial protamine P1 genes.";
RL   Proc. R. Soc. B 259:7-14(1995).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
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DR   EMBL; L35448; AAA74612.1; -; Genomic_DNA.
DR   RefSeq; NP_001028139.1; NM_001032967.1.
DR   AlphaFoldDB; P67836; -.
DR   PRIDE; P67836; -.
DR   Ensembl; ENSMODT00000006452; ENSMODP00000006320; ENSMODG00000005135.
DR   GeneID; 497042; -.
DR   KEGG; mdo:497042; -.
DR   CTD; 5619; -.
DR   HOGENOM; CLU_2978527_0_0_1; -.
DR   OMA; MARYICC; -.
DR   Proteomes; UP000002280; Chromosome 6.
DR   Bgee; ENSMODG00000005135; Expressed in spermatid and 13 other tissues.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR   InterPro; IPR000221; Protamine_P1.
DR   PROSITE; PS00048; PROTAMINE_P1; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Reference proteome; Spermatogenesis.
FT   CHAIN           1..58
FT                   /note="Sperm protamine P1"
FT                   /id="PRO_0000191495"
FT   REGION          1..58
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   58 AA;  7941 MW;  287A58B2CD6C4E52 CRC64;
     MARYRRRSRS RSRSRYGRRR RRSRSRRRRS RRRRRRRGRR GRGYHRRSPH RRRRRRRR