ID   HSP1_ORCOR              Reviewed;          47 AA.
AC   P24713;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Sperm protamine P1;
DE   AltName: Full=Cysteine-rich protamine;
GN   Name=PRM1; Synonyms=P1;
OS   Orcinus orca (Killer whale) (Delphinus orca).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Delphinidae; Orcinus.
OX   NCBI_TaxID=9733;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1741296; DOI=10.1093/nar/20.3.609;
RA   Adroer R., Queralt R., Ballabriga J., Oliva R.;
RT   "Nucleotide sequence of the protamine P1 gene from the whale Orcinus orca
RT   predicts a unique N-terminal amino-acid motif.";
RL   Nucleic Acids Res. 20:609-609(1992).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
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DR   EMBL; Z11496; CAA77572.1; -; Genomic_DNA.
DR   PIR; S22828; S22828.
DR   AlphaFoldDB; P24713; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR   InterPro; IPR000221; Protamine_P1.
DR   Pfam; PF00260; Protamine_P1; 1.
DR   PROSITE; PS00048; PROTAMINE_P1; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT   CHAIN           1..47
FT                   /note="Sperm protamine P1"
FT                   /id="PRO_0000191516"
SQ   SEQUENCE   47 AA;  6029 MW;  1D147FF0DA082B70 CRC64;
     MARNRCRSPS QSRCRRPRRR CRRRIRCCRR QRRVCCRRYT TTRCARQ