HSP1_PARRT
ID HSP1_PARRT Reviewed; 63 AA.
AC Q71V11;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 41.
DE RecName: Full=Sperm protamine P1;
GN Name=PRM1;
OS Paramurexia rothschildi (Broad-striped dasyure) (Murexia rothschildi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Murexia.
OX NCBI_TaxID=418657;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Armstrong L.A., Krajewski C., Westerman M.;
RT "Phylogeny of the dasyurid marsupial genus Antechinus based on cytochrome-
RT b, 12S-rRNA, and protamine-P1 genes.";
RL J. Mammal. 79:1379-1389(1998).
CC -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC during the haploid phase of spermatogenesis. They compact sperm DNA
CC into a highly condensed, stable and inactive complex (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Testis.
CC -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF038302; AAC15629.1; -; Genomic_DNA.
DR AlphaFoldDB; Q71V11; -.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR InterPro; IPR000221; Protamine_P1.
DR PROSITE; PS00048; PROTAMINE_P1; 1.
PE 2: Evidence at transcript level;
KW Chromosome; Developmental protein; Differentiation; DNA condensation;
KW DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT CHAIN 1..63
FT /note="Sperm protamine P1"
FT /id="PRO_0000191501"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 63 AA; 8697 MW; 99A6BEA7CBB77964 CRC64;
MARYRRHSRS RSRSRYRRRR RRRSRHHNRR RTYRRSRRHS RRRRGRRRGY SRRRYSRRGR
RRY