ID   HSP1_SAISC              Reviewed;          50 AA.
AC   Q9GKQ1;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=Sperm protamine P1;
GN   Name=PRM1;
OS   Saimiri sciureus (Common squirrel monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC   Saimiriinae; Saimiri.
OX   NCBI_TaxID=9521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Karanth P.K., Stewart C.-B., Holt R.A., de Koning J., Messier W.;
RT   "Positive Darwinian selection on the lineage leading to humans.";
RL   Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBUNIT: Cross-linked by interchain disulfide bonds around the DNA-
CC       helix. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
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DR   EMBL; AF119241; AAG42165.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9GKQ1; -.
DR   PRIDE; Q9GKQ1; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR   InterPro; IPR000221; Protamine_P1.
DR   Pfam; PF00260; Protamine_P1; 1.
DR   PROSITE; PS00048; PROTAMINE_P1; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; Disulfide bond;
KW   DNA condensation; DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT   CHAIN           1..50
FT                   /note="Sperm protamine P1"
FT                   /id="PRO_0000191553"
SQ   SEQUENCE   50 AA;  6849 MW;  82FE7F3A307AF5E3 CRC64;
     MARYRCCRSR SRSRCYRRRR RCRTRRRRCC RRRRARRCCR RRYKLRCRRY