ID   HSP1_SARHA              Reviewed;          62 AA.
AC   P62486; P42151;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Sperm protamine P1;
GN   Name=PRM1;
OS   Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX   NCBI_TaxID=9305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Sperm;
RX   PubMed=7700877; DOI=10.1098/rspb.1995.0002;
RA   Retief J.D., Krajewski C., Westerman M., Winkfein R.J., Dixon G.H.;
RT   "Molecular phylogeny and evolution of marsupial protamine P1 genes.";
RL   Proc. R. Soc. B 259:7-14(1995).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
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DR   EMBL; L35324; AAA74608.1; -; Genomic_DNA.
DR   AlphaFoldDB; P62486; -.
DR   Ensembl; ENSSHAT00000034032; ENSSHAP00000025643; ENSSHAG00000023877.
DR   HOGENOM; CLU_2903624_0_0_1; -.
DR   OMA; MARYICC; -.
DR   Proteomes; UP000007648; Unassembled WGS sequence.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR   InterPro; IPR000221; Protamine_P1.
DR   PROSITE; PS00048; PROTAMINE_P1; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Reference proteome; Spermatogenesis.
FT   CHAIN           1..62
FT                   /note="Sperm protamine P1"
FT                   /id="PRO_0000191554"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   62 AA;  8541 MW;  2CB7AD3D85AA5F30 CRC64;
     MARYRRRSRS RSRSRYRRRR RRRSRGRRRR TYRRSRRHSR RRRGRRRGYS RRRYSRRGRR
     RY