ID   HSP1_TACAC              Reviewed;          69 AA.
AC   P35311;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Sperm protamine P1;
GN   Name=PRM1; Synonyms=PRM-1;
OS   Tachyglossus aculeatus aculeatus (Southeast Australian short-beaked
OS   echidna).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Monotremata; Tachyglossidae; Tachyglossus.
OX   NCBI_TaxID=49271;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8269934; DOI=10.1111/j.1432-1033.1993.tb18396.x;
RA   Retief J.D., Winkfein R.J., Dixon G.H.;
RT   "Evolution of the monotremes. The sequences of the protamine P1 genes of
RT   platypus and echidna.";
RL   Eur. J. Biochem. 218:457-461(1993).
CC   -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC       during the haploid phase of spermatogenesis. They compact sperm DNA
CC       into a highly condensed, stable and inactive complex.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- TISSUE SPECIFICITY: Testis.
CC   -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
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DR   EMBL; Z26848; CAA81444.1; -; Genomic_DNA.
DR   PIR; S39424; S39424.
DR   AlphaFoldDB; P35311; -.
DR   GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR   InterPro; IPR000221; Protamine_P1.
DR   PROSITE; PS00048; PROTAMINE_P1; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; Developmental protein; Differentiation; DNA condensation;
KW   DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT   CHAIN           1..69
FT                   /note="Sperm protamine P1"
FT                   /id="PRO_0000191576"
FT   REGION          1..69
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   69 AA;  8804 MW;  8797BF9BD48407D5 CRC64;
     MARFRPSRSR SRSLYRRRRR SRRQRSRRGG RQTGPRKITR RGRGRGKSRR RRGRRSMRSS
     RRRRRRRRN