HSP1_THYST
ID HSP1_THYST Reviewed; 62 AA.
AC Q9GLQ8;
DT 16-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 49.
DE RecName: Full=Sperm protamine P1;
GN Name=PRM1;
OS Thylogale stigmatica (Red-legged pademelon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Diprotodontia; Macropodidae; Thylogale.
OX NCBI_TaxID=9328;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Burk A., Springer M.S.;
RT "Intergeneric relationships among Macropodoidea (Metatheria: Diprotodontia)
RT and the chronicle of kangaroo evolution.";
RL J. Mammal. Evol. 7:213-237(2000).
CC -!- FUNCTION: Protamines substitute for histones in the chromatin of sperm
CC during the haploid phase of spermatogenesis. They compact sperm DNA
CC into a highly condensed, stable and inactive complex.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC -!- TISSUE SPECIFICITY: Testis.
CC -!- SIMILARITY: Belongs to the protamine P1 family. {ECO:0000305}.
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DR EMBL; AF187534; AAG27951.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9GLQ8; -.
DR GO; GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR GO; GO:0035092; P:sperm DNA condensation; IEA:InterPro.
DR InterPro; IPR000221; Protamine_P1.
DR PROSITE; PS00048; PROTAMINE_P1; 1.
PE 2: Evidence at transcript level;
KW Chromosome; Developmental protein; Differentiation; DNA condensation;
KW DNA-binding; Nucleosome core; Nucleus; Spermatogenesis.
FT CHAIN 1..62
FT /note="Sperm protamine P1"
FT /id="PRO_0000191578"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 62 AA; 8649 MW; DEB462499589DDBC CRC64;
MARYRHSRSR SRSRYRRRRR RRSRYRSRRR RYRGRRRRRS RRGRRRRGYS CRRYSRRRRR
RY