ID   HSP30_NEUCR             Reviewed;         228 AA.
AC   P19752; Q7RVJ4;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-MAY-2022, entry version 126.
DE   RecName: Full=30 kDa heat shock protein;
GN   Name=hsp30; ORFNames=NCU09364;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=2144284; DOI=10.1016/s0021-9258(18)55415-6;
RA   Plesofsky-Vig N., Brambl R.;
RT   "Gene sequence and analysis of hsp30, a small heat shock protein of
RT   Neurospora crassa which associates with mitochondria.";
RL   J. Biol. Chem. 265:15432-15440(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Note=Associated with mitochondria at
CC       heat shock temperature, soluble at normal growth temperature
CC       (reversibility).
CC   -!- MISCELLANEOUS: The N-terminal putative helical domain may be the site
CC       through which HSP30 binding to mitochondrial membrane is regulated.
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00285}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M55672; AAA33589.1; -; Genomic_DNA.
DR   EMBL; CM002236; EAA34538.1; -; Genomic_DNA.
DR   PIR; A38360; A38360.
DR   RefSeq; XP_963774.1; XM_958681.3.
DR   AlphaFoldDB; P19752; -.
DR   SMR; P19752; -.
DR   STRING; 5141.EFNCRP00000009461; -.
DR   EnsemblFungi; EAA34538; EAA34538; NCU09364.
DR   GeneID; 3879923; -.
DR   KEGG; ncr:NCU09364; -.
DR   VEuPathDB; FungiDB:NCU09364; -.
DR   HOGENOM; CLU_046737_1_1_1; -.
DR   InParanoid; P19752; -.
DR   OMA; RTITFPA; -.
DR   Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   InterPro; IPR045045; RTM2-like.
DR   PANTHER; PTHR43670; PTHR43670; 1.
DR   Pfam; PF00011; HSP20; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
DR   PROSITE; PS01031; SHSP; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Stress response.
FT   CHAIN           1..228
FT                   /note="30 kDa heat shock protein"
FT                   /id="PRO_0000126007"
FT   DOMAIN          49..228
FT                   /note="sHSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00285"
FT   REGION          34..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          117..136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          144..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        35..53
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        120..136
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        144..162
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   228 AA;  25264 MW;  4F4A7D64DDBB759E CRC64;
     MALFPRGFYG SYGSDPSFTN LFRLLDDFDT YTREVQGSAP ETGSRRHTQP TRTFSPKFDV
     RETEQTYELH GELPGIDRDN VQIEFTDPQT IVIRGRVERN YTAGTPPAQV AGVLTEKGEP
     HSPAAHHATV EDDVDEDNRS VATTATGANN QNNQQVAQRA SAPTTEEKPK APAEKYWVSE
     RSIGEFSRTF NFPGRVDQNA VSASLNNGIL TITVPKAKKH ETIRIAIN