ID   HSP70_HYDVU             Reviewed;         654 AA.
AC   Q05944;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Heat shock 70 kDa protein;
GN   Name=HSP70.1;
OS   Hydra vulgaris (Hydra) (Hydra attenuata).
OC   Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC   Aplanulata; Hydridae; Hydra.
OX   NCBI_TaxID=6087;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1483453; DOI=10.1111/j.1432-1033.1992.tb17469.x;
RA   Gellner K., Praetzel G., Bosch T.C.G.;
RT   "Cloning and expression of a heat-inducible hsp70 gene in two species of
RT   Hydra which differ in their stress response.";
RL   Eur. J. Biochem. 210:683-691(1992).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; M84019; AAA29213.1; -; Genomic_DNA.
DR   PIR; S27004; S27004.
DR   AlphaFoldDB; Q05944; -.
DR   SMR; Q05944; -.
DR   PRIDE; Q05944; -.
DR   Proteomes; UP000694840; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome; Stress response.
FT   CHAIN           1..654
FT                   /note="Heat shock 70 kDa protein"
FT                   /id="PRO_0000078290"
FT   REGION          621..654
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   654 AA;  71468 MW;  5BC1EA4BA1E640FB CRC64;
     MSKAPAIGID LGTTYSCVGV FQHGKVEIIA NEQGNRTTPS YVAFTDTERL IGDAAKNQVA
     MNPSNTVFDA KRLIGRKFND PSVTSDRKHW PFNVIDDGSR PKIQVEFKGE TKSFYPEEIS
     SMVLLKMEEI ADAYLGKKVT DVVITVPAYF NDSQRQATKD AGVIAGLNVL RIINEPTAAA
     IAYGLDKKVG TEKNVLIFDL GGGTFDVSIL AIEDGIFEIK STAGDTHLGG EDFDNRLVNH
     FVDEFKRKHK KDISSNKRAL RRLRTACERA KRTLSASTQA SVEIDSLFDG IDFYTSITRA
     RFEELCIDLF RGTLGPVADA IRGAGKNSSG QNFSKSDIHE VVLVGGSTRI PKVQSLLQEF
     FNGKELNKSI NPDEAVAYGA AVQAAILAGD KHEAVQDLLL LDVAPLSLGI ETAGGVFTPL
     IKRNTTVPTK YSQVFTTYSD NQPGVLIQVF EGERSMTAHN NLLGKFELSG IPLAPRGVPQ
     IEVTFDVDAN GILNVSALDK STGKENKITI TNDKGRLSKE DIERMVQEAE KYKADDELQR
     DKVQAKNSLE SYCYNMKQTV EDEKVKGKIS EEDKKTIIKK CNETVEWVDK NQTAEKDQYE
     HKQKELEKVC NPIITKLYQA GGGMPGGMPG GMPGGMPGSG SKASSGGPTI EEVD