ID   HSP70_MAIZE             Reviewed;         645 AA.
AC   P11143;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 2.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Heat shock 70 kDa protein;
GN   Name=HSP70;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-70, AND NUCLEOTIDE SEQUENCE [GENOMIC
RP   DNA] OF 72-645.
RX   PubMed=16453670; DOI=10.1002/j.1460-2075.1986.tb04233.x;
RA   Rochester D.E., Winer J.A., Shah D.M.;
RT   "The structure and expression of maize genes encoding the major heat shock
RT   protein, hsp70.";
RL   EMBO J. 5:451-458(1986).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; X03658; CAA27293.1; -; Genomic_DNA.
DR   EMBL; X03697; CAA27330.1; -; Genomic_DNA.
DR   EMBL; X03714; CAA27340.1; -; Genomic_DNA.
DR   PIR; A25089; A25089.
DR   STRING; 4577.GRMZM2G310431_P01; -.
DR   PaxDb; P11143; -.
DR   PRIDE; P11143; -.
DR   MaizeGDB; 25911; -.
DR   eggNOG; KOG0101; Eukaryota.
DR   Proteomes; UP000007305; Unplaced.
DR   ExpressionAtlas; P11143; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IBA:GO_Central.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0031072; F:heat shock protein binding; IBA:GO_Central.
DR   GO; GO:0051787; F:misfolded protein binding; IBA:GO_Central.
DR   GO; GO:0044183; F:protein folding chaperone; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0034620; P:cellular response to unfolded protein; IBA:GO_Central.
DR   GO; GO:0051085; P:chaperone cofactor-dependent protein refolding; IBA:GO_Central.
DR   GO; GO:0042026; P:protein refolding; IBA:GO_Central.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome; Stress response.
FT   CHAIN           1..645
FT                   /note="Heat shock 70 kDa protein"
FT                   /id="PRO_0000078352"
FT   REGION          620..645
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        4
FT                   /note="G -> S (in Ref. 1; CAA27293)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        14
FT                   /note="G -> E (in Ref. 1; CAA27340)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        22
FT                   /note="V -> L (in Ref. 1; CAA27293)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        45
FT                   /note="A -> G (in Ref. 1; CAA27293)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   645 AA;  70573 MW;  7AF977611F5BAAC4 CRC64;
     MAKGEGPAIG IDLGTTYSCV GVWQHDRVEI IANDQGNRTT PSYVAFTDTE RLIGDAAKNQ
     VAMNPTNTVF DAKRLIGRRF SSPAVQSSMK LWPSRHLGLG DKPMIVFNYK GEEKQFAAEE
     ISSMVLIKMK EIAEAYLGST IKNAVVTVPA YFNDSQRQAT KDAGVIAGLN VMRIINEPTA
     AAIAYGLDKK ATSSGEKNVL IFDLGGGTFD VSLLTIEEGI FEVKATAGDT HLGGEDFDNR
     MVNHFVQEFK RKNKKDISGN PRALRRLRTA CERAKRTLSS TAQTTIEIDS LFEGIDFTPR
     SSRARFEELN MDLFRKCMEP VEKCLRDAKM DKSSVHDVVL VGGSTRIPKV QQLQDFFNGK
     ELCKSINPDE AVAYGAAVQA AILSGEGNER SDLLLLDVTP LSLGLETAGG VMTVLIPRNT
     TIPTKKEQVF STYSDNQPGV LIQVYEGERA RTKDNNLLGK FELSGIPPAP RGVPQITVTF
     DIDVNNILNV SAEDKTTGQK NKITITNDKG RLSKEEIEKM VQEAEKYKAE DEEVKKKVDA
     KNALENYAYN MRNTIKDDKI ASKLPAEDKK KIEDAVDGAI SWLDSNQLAE VEEFEDKMKE
     LEGICNPIIA KMYXGEGAGM GAAAGMDEDA PSGGSGAGPK IEEVD