ID   HSP70_PLACB             Reviewed;         686 AA.
AC   Q05746;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Heat shock 70 kDa protein;
DE            Short=HSP70;
DE   AltName: Full=74.6 kDa protein;
DE   AltName: Full=Cytoplasmic antigen;
OS   Plasmodium cynomolgi (strain Berok).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=5828;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1426134; DOI=10.1016/0014-4894(92)90217-x;
RA   Eckert V., Sanchez L., Cochrane A.H., Enea V.;
RT   "Plasmodium cynomolgi: the hsp 70 gene.";
RL   Exp. Parasitol. 75:323-328(1992).
CC   -!- DEVELOPMENTAL STAGE: Expressed at high levels in the asexual blood
CC       stage forms.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; M90978; AAA29625.1; -; Genomic_DNA.
DR   PIR; A49242; A49242.
DR   AlphaFoldDB; Q05746; -.
DR   SMR; Q05746; -.
DR   PRIDE; Q05746; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Nucleotide-binding; Repeat; Stress response.
FT   CHAIN           1..686
FT                   /note="Heat shock 70 kDa protein"
FT                   /id="PRO_0000078310"
FT   REPEAT          632..635
FT                   /note="1"
FT   REPEAT          636..639
FT                   /note="2"
FT   REPEAT          640..643
FT                   /note="3"
FT   REPEAT          644..647
FT                   /note="4"
FT   REPEAT          648..651
FT                   /note="5"
FT   REPEAT          653..656
FT                   /note="6"
FT   REPEAT          657..660
FT                   /note="7"
FT   REPEAT          663..666
FT                   /note="8"
FT   REPEAT          668..671
FT                   /note="9"
FT   REPEAT          672..675
FT                   /note="10"
FT   REGION          632..675
FT                   /note="10 X 4 AA tandem repeats of G-G-M-P"
FT   REGION          657..686
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   686 AA;  74603 MW;  FF31F448FFCBF286 CRC64;
     MASGKASKPN LPESNIAIGI DLGTTYSCVG VWRNENVDII ANDQGNRTTP SYVAFTDTER
     LIGDAAKNQV ARNPENTVFD AKRLIGRKFT ESSVQSDMKH WPFTVKSGVD EKPMIEVSYQ
     GEKKLFHPEE ISSMVLQKMK ENAEAFLGKS IKNAVITVPA YFNDSQRQAT KDAGTIAGLN
     VMRIINEPTA AAIAYGLHKK GKGEKNILIF DLGGGTFDVS LLTIEDGIFE VKATAGDTHL
     GGEDFDNRLV NFCVEDFKRK NRGKDLSKNS RALRRLRTQC ERAKRTLSSS TQATIEIDSL
     FEGIDYSVTV SRARFEELCI DYFRDTLIPV EKVLKDAMMD KKSVHEVVLV GGSTRIPKIQ
     TLIKEFFNGK EACRSINPDE AVAYGAAVQA AILSGDQSNA VQDLLLLDVC SLSLGLETAG
     GVMTKLIERN TTIPAKKSQI FTTYADNQPG VLIQVYEGER ALTKDNNLLG KFHLDGIPPA
     PRKVPQIEVT FDIDANGILN VTAVEKSTGK QNHITITNDK GRLSPEEIDR MVNDAEKYKA
     EDEENKKRIE ARNSLENYCY GVKSSLEDQK IKEKLQPSEI ETCMKSITTI LEWLEKNQLA
     SKEEYESKQK EAESVCAPIM SKIYQDVGGA AGGMPGGMPG GMPGGMPGGM PGGGMPGGMN
     FPGGMPGGGM PGGAPAGSGP TVEEVD