ID   HSP70_PLEWA             Reviewed;         645 AA.
AC   Q91291;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Heat shock 70 kDa protein;
DE            Short=HSP70;
GN   Name=HSP70;
OS   Pleurodeles waltl (Iberian ribbed newt).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Caudata; Salamandroidea; Salamandridae; Pleurodelinae;
OC   Pleurodeles.
OX   NCBI_TaxID=8319;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8187647; DOI=10.1242/dev.119.3.921;
RA   Billoud B., Rodriguez-Martin M.L., Berard L., Moreau N., Angelier N.;
RT   "Constitutive expression of a somatic heat-inducible hsp70 gene during
RT   amphibian oogenesis.";
RL   Development 119:921-932(1993).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; X71951; CAA50749.1; -; mRNA.
DR   PIR; I51129; I51129.
DR   AlphaFoldDB; Q91291; -.
DR   SMR; Q91291; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Nucleotide-binding; Stress response.
FT   CHAIN           1..645
FT                   /note="Heat shock 70 kDa protein"
FT                   /id="PRO_0000078289"
FT   REGION          615..645
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        625..645
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   645 AA;  70977 MW;  FA5111ACFDF3413C CRC64;
     MSAPKGVAFG IDLGTTYSCV GVFQHGKVEI IANNQGNRTT PSYVAFTDTE RLIGAPAKNQ
     VSLNPQNTVF DAKRLIGRKF NDTVVQADMK HWPFKVVSDE WKPKVQVEYK GDNKTFFPDE
     VSSMVLIKMK EIAEAYLGHL VSNAVITVPS YLTASQRQAT KDAGVLAGLN VLSIVNEPTA
     AAIAYDLDKA GRGELNVLIF DLGGGTFDVS ILTIDDGIFE VKATAGDTHL GGEDFDNRMV
     NHFHEPFKRK HKKDITKNKR AVRRLRTACE RAKRTLSSST QASIEIDSLF EGIDFYTSIT
     RARFEELCAD LFRGPLEPVE KALRDAKLDK AQIHEIVLVG GSTRIPKIQK LLQDFFNGRE
     LNKSINPDEA VAYGAAVQAA ILMGDKSENL QDLLLLDVAP LSLGLETAGG VMTVLIKRNS
     TIPTKQTQIF TTYSDNQPGV LIQVYEGERA MTKDNSLLGK FELSGIPPAP RGVPQIEVTF
     DIDANGILNV SAVDKSSGKQ NKITITNDKG RLSKEEIERM VQEAERYKAD DEAQREKVSA
     KNTLESIAFN MKSTVEGDNL KDKISEDDRK KIVDKCNQTI SWMENNQMAE KEEYEHQQKE
     LEKVCNSIIT KLYQGGMPGG MPSGSSGAQA RQGSSSTGPT IEEVD