ID   HSP70_PYRSA             Reviewed;         649 AA.
AC   P37899;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Heat shock 70 kDa protein;
GN   Name=HSP70;
OS   Pyrenomonas salina.
OG   Nucleomorph.
OC   Eukaryota; Cryptophyceae; Pyrenomonadales; Pyrenomonadaceae; Pyrenomonas.
OX   NCBI_TaxID=3034;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8208251; DOI=10.1007/bf00284209;
RA   Hofmann C.J.B., Rensing S.A., Haeuber M.M., Martin W.F., Mueller S.B.,
RA   Couch J., McFadden G.I., Igloi G.L., Maier U.-G.;
RT   "The smallest known eukaryotic genomes encode a protein gene: towards an
RT   understanding of nucleomorph functions.";
RL   Mol. Gen. Genet. 243:600-604(1994).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; X72621; CAA51197.1; -; Genomic_DNA.
DR   PIR; S42488; S42488.
DR   AlphaFoldDB; P37899; -.
DR   SMR; P37899; -.
DR   PRIDE; P37899; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Stress response.
FT   CHAIN           1..649
FT                   /note="Heat shock 70 kDa protein"
FT                   /id="PRO_0000078313"
FT   REGION          620..649
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        620..639
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   649 AA;  72080 MW;  B627B08FF90C9164 CRC64;
     MENKIEGVAI GIDLGTTYSC VGVWLHDRVE VIANDQGNRT TPSYVAFTET ERLIGDSAKN
     QVAMNPDNTV FDAKRLIGRR FQDPAVQEDV KPFPFKVICK DGDKPAVEVK YKGETKIFAP
     EEISSMVLLK MKEIAESFLG KEVKNAVITV PAYFNDSQRQ ATKDAGAITG LNVLRIINEP
     TAAAIAYGLD KKTSGSKSER NVLIFDLGGG TFDVSLLTIE EGIFEVKATA GDTHLGGEDF
     DSRLVNFFVS EFKRKYKKDV TSNARSLRRL RTACERAKRT LSSGTQTTVE IDSLIDGIDY
     YASITRAKFE ELCMDLFRGT SEPVEKVLRD SKISKSEIHD VVLVGGSTRI PKVQQLLIDY
     FNGKELCKNI NPDEAVAYGA AVQAAILAGD TSEKMDLLLL DVSPLSLGLE TAGGVMTVLI
     KRNTTIPTKK TQVFSTYADN QPGVLIQVFE GERSRTKDNN ILGKFELTGI PPAPRGVPQI
     EVTFDIDANG ILNVSASDKS TGKSNKITIT NDKGRLSKEE IERMVEEAEK YKTEDEKLDK
     KLEAKNSLEN YAYNIRNTVR DEKLKEKIQE EDKKSIEEKV KEVLEFIETN EDLEKEEYEE
     KEKELKNFAN PIISKLYQQG SVPDMGNFST GQNEQDDNAN MGPKIEEVG