ID   HSP70_THEAN             Reviewed;         646 AA.
AC   P16019; Q4UDK8;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 2.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Heat shock 70 kDa protein;
DE   AltName: Full=70 kDa heat shock protein;
DE   AltName: Full=HSP 70.1;
GN   ORFNames=TA11610;
OS   Theileria annulata.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC   Theileriidae; Theileria.
OX   NCBI_TaxID=5874;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2515435; DOI=10.1016/0166-6851(89)90099-6;
RA   Mason P.J., Shiels B.R., Tait A., Beck P., Hall R.;
RT   "Sequence and expression of a gene from Theileria annulata coding for a 70-
RT   kilodalton heat-shock protein.";
RL   Mol. Biochem. Parasitol. 37:27-36(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ankara;
RX   PubMed=15994557; DOI=10.1126/science.1110418;
RA   Pain A., Renauld H., Berriman M., Murphy L., Yeats C.A., Weir W.,
RA   Kerhornou A., Aslett M., Bishop R., Bouchier C., Cochet M., Coulson R.M.R.,
RA   Cronin A., de Villiers E.P., Fraser A., Fosker N., Gardner M., Goble A.,
RA   Griffiths-Jones S., Harris D.E., Katzer F., Larke N., Lord A., Maser P.,
RA   McKellar S., Mooney P., Morton F., Nene V., O'Neil S., Price C.,
RA   Quail M.A., Rabbinowitsch E., Rawlings N.D., Rutter S., Saunders D.,
RA   Seeger K., Shah T., Squares R., Squares S., Tivey A., Walker A.R.,
RA   Woodward J., Dobbelaere D.A.E., Langsley G., Rajandream M.A., McKeever D.,
RA   Shiels B., Tait A., Barrell B.G., Hall N.;
RT   "Genome of the host-cell transforming parasite Theileria annulata compared
RT   with T. parva.";
RL   Science 309:131-133(2005).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; J04653; AAA30130.1; -; Genomic_DNA.
DR   EMBL; CR940348; CAI74831.1; -; Genomic_DNA.
DR   PIR; A44985; A44985.
DR   RefSeq; XP_952563.1; XM_947470.1.
DR   AlphaFoldDB; P16019; -.
DR   SMR; P16019; -.
DR   STRING; 5874.XP_952563.1; -.
DR   PRIDE; P16019; -.
DR   GeneID; 3861887; -.
DR   KEGG; tan:TA11610; -.
DR   VEuPathDB; PiroplasmaDB:TA11610; -.
DR   eggNOG; KOG0101; Eukaryota.
DR   InParanoid; P16019; -.
DR   OMA; KANPIMM; -.
DR   OrthoDB; 288077at2759; -.
DR   Proteomes; UP000001950; Chromosome 2.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome; Stress response.
FT   CHAIN           1..646
FT                   /note="Heat shock 70 kDa protein"
FT                   /id="PRO_0000078320"
FT   REGION          613..646
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        450
FT                   /note="M -> L (in Ref. 1; AAA30130)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        624..625
FT                   /note="SG -> GA (in Ref. 1; AAA30130)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   646 AA;  71007 MW;  E768C1737F414B56 CRC64;
     MTGPAIGIDL GTTYSCVAVY KDNNVEIIPN DQGNRTTPSY VAFTDTERLI GDAAKNQEAR
     NPENTIFDAK RLIGRKFDDR TVQEDMKHWP FKVTNGPNGK PNIEVTFQGE KKTFHAEEIS
     SMVLTKMKEI AESFLGKSVK DVVITVPAYF NDSQRQATKD AGTIAGLNVM RIINEPTAAA
     IAYGLDKKGG GEKNVLIFDL GGGTFDVSIL TIEDGIFEVK ATAGDTHLGG EDFDNLLVEH
     CVRDFMRLNN GKNISSNKRA LRRLRTHCER AKRVLSSSTQ ATIELDSLYE GIDYNTTISR
     ARFEELCNEK FRSTLVPVEK ALESSGLDKR SIHEVVLVGG STRIPKIQTL IKNFFNGKEP
     CRSINPDEAV AYGAAVQAAI LSGNQSEKIQ ELLLLDVAPL SLGLETAGGV MTVLIKRNTT
     IPTKKNQIFT TNEDRQEGVL IQVFEGERAM TKDNNLLGKF HLTGIAPAPR GVPQIEVTFD
     IDANGILNVT AMDKSTGKSE HVTITNDKGR LSQEEIDRMV EEAEKYKEED EKRRRCVESR
     HKLENYCYSM KNTLSEDQVK QKLGADEVDS ALSTITDALK WVEANQLAEH DEYEDKLKHV
     EGVCNPLVTK LYQSGAAPGG PDMSGGFPGG AAPPPQSSGP TVEEVD