ID   HSP71_PARBA             Reviewed;         649 AA.
AC   P87047;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Heat shock 70 kDa protein 1;
GN   Name=HSP70-1;
OS   Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS   brasiliensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND INDUCTION.
RC   STRAIN=ATCC MYA-826 / Pb01;
RX   PubMed=10096073; DOI=10.1046/j.1365-2958.1999.01236.x;
RA   da Silva S.P., Borges-Walmsley M.I., Pereira I.S., Soares C.M.,
RA   Walmsley A.R., Felipe M.S.S.;
RT   "Differential expression of an hsp70 gene during transition from the
RT   mycelial to the infective yeast form of the human pathogenic fungus
RT   Paracoccidioides brasiliensis.";
RL   Mol. Microbiol. 31:1039-1050(1999).
CC   -!- INDUCTION: Preferentially expressed in yeast cells, the host parasitic
CC       phase (at protein level). {ECO:0000269|PubMed:10096073}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
CC   -!- CAUTION: The DNA coding for this protein is not found in the complete
CC       genome of strain ATCC MYA-826 / Pb01. {ECO:0000305}.
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DR   EMBL; U91560; AAB53051.1; -; Genomic_DNA.
DR   AlphaFoldDB; P87047; -.
DR   SMR; P87047; -.
DR   PRIDE; P87047; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Chaperone; Nucleotide-binding; Stress response.
FT   CHAIN           1..649
FT                   /note="Heat shock 70 kDa protein 1"
FT                   /id="PRO_0000078374"
FT   REGION          614..649
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   649 AA;  70504 MW;  1F64FFE0A8679942 CRC64;
     MAPAIGIDLG TTYSCVGIFR DDRIEIIANE QGNRNTPSFV AFTDTERLIG DAAKNQVAMN
     PQTVFEAKRL IGRKFADPEV QADMKHFPFK ITDKGGNPKI QVEFRGEGKH FTPEGISSMF
     RRKKREIAES YLGGTVNNAV VTVPAYFNDS QRQVTKDAGL IAGLNVLRII NEPTAAAIAY
     GLDKKAEGER NVLILDLGGG TFDVSLLTIE EGIFEVKSTA GDTHFGGEDF DNRLVNHFVN
     EFKRKHKKDL SSNARALRRL RTACERAKRT LSSAAQTSIE IDSLYEGIDF YTSITRARFE
     ELCQDLFRST MDPVERVLRD AKIDKSSVHE IVLVGGSTRI PRIQKLVSDF FNGKEPNKSI
     NPDEAVAYGA AVQAAILSGD STSKSTNEIL LLDVAPLSVG IETAGGVMTP LIKRNTTIPT
     KKSETFSTFA DNQPGVLIQV FEGERARTKE NNLLGKFELT GIPPAPGVPQ IEVTFDVDAN
     GIMNVSALEK GIGKTNKIVI TNDKGRLSKE EIERMLAEAE KYKAEDEAEA SRISAKNGLE
     SYAYSLRNTI SDSKVDEKLD ASDKEKLKTE IDKTVSWLDE NQTATKEEFE AQQKELESVA
     NPIMMKFYGA GGAPGAGFPG AGGPGGFPGA GVGGAHSGGD DGPTVEEVD