ID   HSP72_PARLI             Reviewed;         372 AA.
AC   P22623;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Heat shock 70 kDa protein II;
DE            Short=HSP70 II;
DE   Flags: Fragment;
GN   Name=HSP70II;
OS   Paracentrotus lividus (Common sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Echinidae; Paracentrotus.
OX   NCBI_TaxID=7656;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Gonad;
RX   PubMed=2269441; DOI=10.1016/0378-1119(90)90267-u;
RA   la Rosa M., Sconzo G., Giudice G., Roccheri M.C., di Carlo M.;
RT   "Sequence of a sea urchin hsp70 gene and its 5' flanking region.";
RL   Gene 96:295-300(1990).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; X16544; CAA34544.1; -; Genomic_DNA.
DR   PIR; PQ0138; PQ0138.
DR   AlphaFoldDB; P22623; -.
DR   SMR; P22623; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Stress response.
FT   CHAIN           1..>372
FT                   /note="Heat shock 70 kDa protein II"
FT                   /id="PRO_0000078316"
FT   NON_TER         372
SQ   SEQUENCE   372 AA;  41347 MW;  5F8C1C590527A659 CRC64;
     MAKAPAVGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL IGDAAKNKTA
     SNPYRSLDAK RLIGRNFSDT NVKADMKHWP FTVIEEGGRP KIKIEFKGES KTFYAEEISS
     MVLLKMKETA EAYLGKESVT DAVVTVPAYF NDSQRQATKE CGVISGMNIL RIINEPTAAA
     IAYGLDKKGG AERNVLIFDL VGGTFDVSVL TIEEGIFEVK STSRDTHLGG EDFDNRMVTH
     SSPEFKRKHK KDITPNKRAV RRLRTACERA KRTLSSSTQA KIEIDSLFEG IDYYTSVTRA
     RFEELNSDLF RGTLEPVENA LRDAKLDKEK IHEIVLVGGS TRIPKIQKLQ DFFHGKELNK
     SINPDEAVAI VQ