ID   HSP74_PARLI             Reviewed;         639 AA.
AC   Q06248;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Heat shock 70 kDa protein IV;
DE            Short=HSP70 IV;
GN   Name=HSP70IV;
OS   Paracentrotus lividus (Common sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Echinidae; Paracentrotus.
OX   NCBI_TaxID=7656;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1339375; DOI=10.1016/0378-1119(92)90143-d;
RA   Sconzo G., Scardina G., Ferraro M.G.;
RT   "Characterization of a new member of the sea urchin Paracentrotus lividus
RT   hsp70 gene family and its expression.";
RL   Gene 121:353-358(1992).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; X61379; CAA43653.1; -; Genomic_DNA.
DR   PIR; JC1391; JC1391.
DR   AlphaFoldDB; Q06248; -.
DR   SMR; Q06248; -.
DR   PRIDE; Q06248; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF100934; SSF100934; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Stress response.
FT   CHAIN           1..639
FT                   /note="Heat shock 70 kDa protein IV"
FT                   /id="PRO_0000078317"
FT   REGION          609..639
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   639 AA;  69750 MW;  40E2F29570808DCC CRC64;
     MESGPAIGID LGTTYSCVGV FQNGKVEIIA NDQGNRTTPS YVAFTDSERL IGDAAKNQVA
     MNPTNTIFDA KRLIGRRFND SSIQADMKHW PFRVINKDGK PMLQAEYMGE TKTLSPEEVS
     SMVLTKMKET AEAYLGKKVT SAVITVPAYF NDAQRQATKD AGVIAGINVL RIINEPTRAA
     LAYGLDKKLT GEKHVLIFDL GGGTFDVSLL AIDDGVFEVL TTAGDTHLGG EDFDNRLVNH
     TSLEFKRKYK KDMRTNPRAI RRLRTAAERA KRTLSSSAQA NIEVDSLFEG IDFYTSISRA
     RFEDLCSDLF RKCLEPVERA ILDAKIDKKK IDTVVLVGGS TRIPKIQKLL QEFLNGKELN
     KSINPDEAVA YGAAVQAAIL SGDKSDEIKD VLLVDVAPLS LGIETAGGVM SKIIERNTRV
     PTKASQTFTT YSDNQPGVSI QVFEGERAMT KDNNRLGQFE LSGIPPAPRG RPKIEVSFDI
     DANGIMHVTA KDESSGRSNK ITITNDSDRL SKDDIDRMIN DAERFKAEDD AQRERINAKN
     QLEGYAFNLK SAVDDAAAQS KLSPGDKETV TKAVNDVLQW LDSNSLADKE EFTYKLEELQ
     KTCSPIMAKM HAGTGGPRGG GPQGFPSGGA GGPTVEEVD