ID   HSP7A_DROSI             Reviewed;         214 AA.
AC   P02826;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Heat shock 70 kDa protein cognate 1;
DE   AltName: Full=Heat shock 70 kDa protein 70C;
DE   Flags: Fragments;
GN   Name=Hsc70-1; Synonyms=Hsc1;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6804941; DOI=10.1073/pnas.79.2.525;
RA   Ingolia T.D., Craig E.A.;
RT   "Drosophila gene related to the major heat shock-induced gene is
RT   transcribed at normal temperatures and not induced by heat shock.";
RL   Proc. Natl. Acad. Sci. U.S.A. 79:525-529(1982).
CC   -!- DEVELOPMENTAL STAGE: Heat shock cognate proteins are expressed
CC       constitutively during normal development.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; J01088; AAA28632.1; -; Genomic_DNA.
DR   EMBL; J01087; AAA28632.1; JOINED; Genomic_DNA.
DR   EMBL; J01089; AAA28633.1; -; Genomic_DNA.
DR   PIR; A03309; A03309.
DR   AlphaFoldDB; P02826; -.
DR   SMR; P02826; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 2.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Nucleotide-binding; Stress response.
FT   CHAIN           1..>214
FT                   /note="Heat shock 70 kDa protein cognate 1"
FT                   /id="PRO_0000078338"
FT   NON_CONS        104..105
FT                   /evidence="ECO:0000305"
FT   NON_TER         214
SQ   SEQUENCE   214 AA;  24001 MW;  7A58EC6E3B91B178 CRC64;
     MPKLPAVGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTESERL IGDAAKNQVA
     MNPNNTIFDA KRLIGRRFDD ATVQSDMKHW PFEAFAENGK PRIRGTFDVS VLTIEDGFEV
     KATAGDTHLG REDFDNRLVN HLVQEFQRKH GKDLGQNKRA LRRLRTACER AKRTLSSSTQ
     ASIEIDSLFE GVDFYTSVTR ARFEELNGDL FRGT