ID   HSP7B_ENCCU             Reviewed;         683 AA.
AC   Q8SSB1;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Heat shock protein homolog ECU03_0520;
GN   OrderedLocusNames=ECU03_0520;
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1;
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], AND
RP   DEVELOPMENTAL STAGE.
RX   PubMed=16691553; DOI=10.1002/pmic.200500796;
RA   Brosson D., Kuhn L., Delbac F., Garin J., Vivares C.P., Texier C.;
RT   "Proteomic analysis of the eukaryotic parasite Encephalitozoon cuniculi
RT   (microsporidia): a reference map for proteins expressed in late sporogonial
RT   stages.";
RL   Proteomics 6:3625-3635(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in late sporogonial stages.
CC       {ECO:0000269|PubMed:16691553}.
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family. {ECO:0000305}.
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DR   EMBL; AL590443; CAD26198.1; -; Genomic_DNA.
DR   RefSeq; NP_597563.1; NM_001040927.1.
DR   AlphaFoldDB; Q8SSB1; -.
DR   SMR; Q8SSB1; -.
DR   STRING; 284813.Q8SSB1; -.
DR   GeneID; 858725; -.
DR   KEGG; ecu:ECU03_0520; -.
DR   VEuPathDB; MicrosporidiaDB:ECU03_0520; -.
DR   HOGENOM; CLU_005965_2_1_1; -.
DR   InParanoid; Q8SSB1; -.
DR   OMA; GCKVQNA; -.
DR   OrthoDB; 288077at2759; -.
DR   Proteomes; UP000000819; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   Gene3D; 1.20.1270.10; -; 1.
DR   Gene3D; 2.60.34.10; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   PANTHER; PTHR19375; PTHR19375; 2.
DR   Pfam; PF00012; HSP70; 2.
DR   SUPFAM; SSF100920; SSF100920; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00297; HSP70_1; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Chaperone; Cytoplasm; Nucleotide-binding; Reference proteome;
KW   Stress response.
FT   CHAIN           1..683
FT                   /note="Heat shock protein homolog ECU03_0520"
FT                   /id="PRO_0000383325"
SQ   SEQUENCE   683 AA;  74830 MW;  9BB58CD959E4F39C CRC64;
     MSEEKAKSNT SRAIGIDLGT TFSCVAGYIS GKVEVITNQD GERTTPSVVS FDENNCTVVG
     TAARNMVGSD PMSVIFDAKR MIGREFDDPK IQNAIKGWPF KVVRYNHREK REEPNKVSEG
     SNSYDNIAIK ITRNGKTNYY APVEISGKVL LYLKNAAEAR LGGTVDSAVV TVPAYFEEPQ
     KDVTKAAATI AGFDPNKVRL LAEPTAAAMA YGHIQTQKNA NFSAKEDVLV FDLGGGTFDV
     SLLDFEFNGA AGSLGIVKAI DGDTFLGGQD FDNLLINYCI SEFLKKNSSI KQSDLKESAL
     LRLRAECTRV KAVLSSATSS AIYVPCFHMT DDLNVQITRA RFELLCDHLF RRCMERTKGC
     LLRSAGVPEV EYSADGSKLL LNPSLEKTLN EVKNNISKVL LVGGSSRIPK IKALLAEYFG
     AHKVIEPVNA DEAVAYGAAY QAASIYSDAV DAGSSLLLID CVPLNLSIET AGGVATALIH
     CGDNIPIKKT ETFTTYEDNQ TAVTINVYEG NRAMCKDNKK IGSFNLDGII AAPRGVPKIE
     VTFDVDHNGI LIVTAQDKQT GKENQIKVTN SQNRLSQEEI ERMTKEARDN EQRDNETKEK
     MGKRMAFDQA ISSFKAFVEK ANNISEEKKS ESLRVIKENE EWLSNAQRPE DFEVEELERR
     SNDFQSFTSD IMKDVGMGGA PAA